{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T14:24:24Z","timestamp":1783779864045,"version":"3.55.0"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T00:00:00Z","timestamp":1582502400000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>During the first week of life, a sudden deterioration in a newborn commonly includes investigations to rule out infections, lung pathologies, cardiac lesions, neurological insults, metabolic disorders or gastrointestinal emergencies. It is unusual, however, to consider malignancy as the primary causative factor. In this case report, we describe a rare and unusual presentation of congenital hepatoblastoma, its complications and management in a neonate with multi-organ dysfunction. A term infant presented with sudden deterioration, hemodynamic instability and an acute abdomen on his 4th day of life. Surgical exploration revealed a ruptured neoplasm that pathology diagnosed as a congenital hepatoblastoma. After the patient was stabilized, chemotherapy was initiated. At present, the patient is 8\u00a0months old and under continuous follow-up of oncology service. This case highlights the importance of considering rare diagnoses including congenital malignancy when investigating and managing a sick newborn with multi-organ dysfunction.<\/jats:p>","DOI":"10.1093\/omcr\/omaa002","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T10:33:27Z","timestamp":1582540407000},"source":"Crossref","is-referenced-by-count":8,"title":["Rare cause of emergency in the first week of life: congenital hepatoblastoma (case report)"],"prefix":"10.1093","volume":"2020","author":[{"given":"Gloria Ha Young","family":"Yoo","sequence":"first","affiliation":[{"name":"Faculty of Pediatrics, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada"},{"name":"Pediatric Department, Jim Pattison Children\u2019 Hospital, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Mugarab-Samedi","sequence":"first","affiliation":[{"name":"Faculty of Pediatrics, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada"},{"name":"Pediatric Department, Jim Pattison Children\u2019 Hospital, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Hansen","sequence":"first","affiliation":[{"name":"Faculty of Pediatrics, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada"},{"name":"Pediatric Department, Jim Pattison Children\u2019 Hospital, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Miller","sequence":"first","affiliation":[{"name":"Faculty of Pediatrics, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada"},{"name":"Pediatric Department, Jim Pattison Children\u2019 Hospital, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Givelichian","sequence":"first","affiliation":[{"name":"Faculty of Pediatrics, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada"},{"name":"Pediatric Department, Jim Pattison Children\u2019 Hospital, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaarthigeyan","family":"Kalaniti","sequence":"first","affiliation":[{"name":"Faculty of Pediatrics, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada"},{"name":"Pediatric Department, Jim Pattison Children\u2019 Hospital, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibasis","family":"Daspal","sequence":"first","affiliation":[{"name":"Faculty of Pediatrics, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada"},{"name":"Pediatric Department, Jim Pattison Children\u2019 Hospital, Royal University Hospital, Saskatoon, SK S7N 0W8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,2,24]]},"reference":[{"key":"2020022405302088500_ref1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1055\/s-2005-872592","article-title":"Neonatal hepatoblastoma: two cases posing a diagnostic dilemma, with a review of the literature","volume":"22","author":"Sallam","year":"2005","journal-title":"Am J Perinatol"},{"key":"2020022405302088500_ref2","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.jpedsurg.2007.07.047","article-title":"Fetal and neonatal hepatic tumors","volume":"42","author":"Isaacs","year":"2007","journal-title":"J Pediatr Surg"},{"key":"2020022405302088500_ref3","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s13244-011-0073-8","article-title":"Congenital tumors: imaging when life just begins","volume":"2","author":"Alamo","year":"2011","journal-title":"Insights 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