{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T22:05:44Z","timestamp":1773180344428,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T00:00:00Z","timestamp":1582848000000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>An 84-year-old woman underwent subtotal stomach pancreatoduodenectomy (PD) for distal cholangiocarcinoma. Over 1000\u00a0ml of serous ascites, which appeared milky after starting a high-protein, low-fat, middle-chain triglyceride diet, was discharged from the inserted drain. On postoperative day (POD) 13, she underwent right hemicolectomy for transverse colonic volvulus, which occurred on POD 9 and was refractory to conservative therapies. Following second surgery, the chylous ascites (CA) amount continued to increase. Octreotide, albumin and diuretics were administered, but the amount of ascites did not decrease. Etilefrine was administered on POD 19; the ascites amount gradually decreased. The drain was removed 3\u00a0days after etilefrine administration. She had no symptoms of abdominal distention after drain removal. Etilefrine\u2019s effectiveness for chylothorax after esophagectomy and CA after distal pancreatectomy has been reported. We present a case of CA successfully treated by etilefrine following PD. Our case highlights etilefrine\u2019s usefulness for CA following PD.<\/jats:p>","DOI":"10.1093\/omcr\/omaa009","type":"journal-article","created":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T15:51:38Z","timestamp":1582905098000},"source":"Crossref","is-referenced-by-count":8,"title":["Successful management of chylous ascites after pancreatoduodenectomy using etilefrine: a case report"],"prefix":"10.1093","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5674-4100","authenticated-orcid":false,"given":"Yusuke","family":"Takahashi","sequence":"first","affiliation":[{"name":"Department of Digestive Surgery, Nagano Municipal Hospital, Nagano, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Seki","sequence":"first","affiliation":[{"name":"Department of Digestive Surgery, Nagano Municipal Hospital, Nagano, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,2,28]]},"reference":[{"key":"2020022810501462800_ref1","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/bjs.9013","article-title":"Chylous ascites after hepatopancreatobiliary surgery","volume":"100","author":"Kuboki","year":"2013","journal-title":"Br J Surg"},{"key":"2020022810501462800_ref2","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/bjs.10316","article-title":"Incidence, risk factors and clinical implications of chyle leak after pancreatic surgery","volume":"104","author":"Strobel","year":"2017","journal-title":"Br J Surg"},{"key":"2020022810501462800_ref3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1046\/j.1442-2050.1999.00021.x","article-title":"Successful management of post-esophagectomy chylothorax\/chyloperitoneum by etilefrine","volume":"12","author":"Guillem","year":"1999","journal-title":"Dis Esophagus"},{"key":"2020022810501462800_ref4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MD.0000000000002214","article-title":"New combined medical treatment with etilefrine and octreotide for chylothorax after esophagectomy a case report and review of the literature","volume":"94","author":"Ohkura","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"2020022810501462800_ref5","first-page":"572","article-title":"A case of successful management of postoperative chylous ascites by combination therapy with octreotide and etilefrine","volume":"45","author":"Koga","year":"2018","journal-title":"Gan To Kagaku Ryoho"},{"key":"2020022810501462800_ref6","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1007\/s11605-008-0619-3","article-title":"Incidence and management of chyle leaks following pancreatic resection: a high volume single-center institutional experience","volume":"12","author":"Assumpcao","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"2020022810501462800_ref7","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.surg.2016.06.058","article-title":"Definition and classification of chyle leak after pancreatic operation: a consensus statement by the international study group on pancreatic surgery","volume":"161","author":"Besselink","year":"2017","journal-title":"Surgery"},{"key":"2020022810501462800_ref8","doi-asserted-by":"crossref","first-page":"386","DOI":"10.4103\/1319-2442.178573","article-title":"Successful management of chylous ascites: a report of two cases","volume":"27","author":"Alam","year":"2016","journal-title":"Saudi J Kidney Dis Transpl"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2020\/2\/omaa009\/32708372\/omaa009.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2020\/2\/omaa009\/32708372\/omaa009.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,28]],"date-time":"2020-02-28T15:51:41Z","timestamp":1582905101000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaa009\/5766269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,1]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaa009","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,2]]},"published":{"date-parts":[[2020,2,1]]},"article-number":"omaa009"}}