{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T22:50:57Z","timestamp":1792363857773,"version":"4.4.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T00:00:00Z","timestamp":1593043200000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>African Histoplasmosis is deep mycosis caused by Histoplasma duboisii and genitourinary involvement is extremely rare. We report a case of African histoplasmosis in a 27-year-old subject with painful penis ulcer. Ulcer edge biopsy had revealed inflammatory granulomas made of epithelioid cells, lymphoplasmocytes, polynuclear eosinophils and giant multinucleated cells, with ovoid yeasts surrounded by a clear halo. PAS and Grocott stains revealed numerous fungal structures with a morphology measuring 7 to 15\u00a0nm. The diagnosis Histoplasma capsulatum var. duboisii was placed and the patient put on itraconazole (400\u00a0mg\/day) for six months with a good course. African histoplasmosis of the subject penis is an extremely rare entity. The diagnosis of certainty often makes use of histology and mycological examination, and makes it possible to eliminate differential diagnoses such as cryptoccocosis, tuberculosis or cancer.<\/jats:p>","DOI":"10.1093\/omcr\/omaa043","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T13:43:49Z","timestamp":1593092629000},"source":"Crossref","is-referenced-by-count":3,"title":["African histoplasmosis of the penis"],"prefix":"10.1093","volume":"2020","author":[{"given":"Tchin","family":"Darr\u00e9","sequence":"first","affiliation":[{"name":"Department of Pathology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matchonna","family":"Kpatcha","sequence":"first","affiliation":[{"name":"Departement of Urology, University Teaching Hospital of Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toukilnan","family":"Djiwa","sequence":"first","affiliation":[{"name":"Department of Pathology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edo\u00e9","family":"Sewa","sequence":"first","affiliation":[{"name":"Departement of Urology, University Teaching Hospital of Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Am\u00e9yo Monique","family":"Dorkenoo","sequence":"first","affiliation":[{"name":"Department of Mycology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouhamed","family":"Kouyat\u00e9","sequence":"first","affiliation":[{"name":"Department of Pathology, University Teaching Hospital of Treichville, Abidjan, Ivory Coast"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gado","family":"Napo-Koura","sequence":"first","affiliation":[{"name":"Department of Pathology, University Teaching Hospital of Lom\u00e9, Lom\u00e9, Togo"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,6,25]]},"reference":[{"key":"2020062509434447300_ref1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1590\/abd1806-4841.20153224","article-title":"Primary cutaneous histoplasmosis developed in the penis of an immunocompetent patient","volume":"90","author":"Paix\u00e3o","year":"2015","journal-title":"An Bras Dermatol."},{"key":"2020062509434447300_ref2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/2323412","article-title":"Histoplasmosis by Histoplasma capsulatum var. duboisii observed at the Laboratory of Pathological Anatomy of Lom\u00e9 in Togo","volume":"2017","author":"Darr\u00e9","year":"2017","journal-title":"J 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histoplasmosis","volume":"167","author":"Pasqualotto","year":"2009","journal-title":"Mycopathologia."},{"key":"2020062509434447300_ref6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006046","article-title":"Histoplasmosis in Africa: an emerging or a neglected disease","volume":"12","author":"Oladele","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"2020062509434447300_ref7","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1177\/1066896916687078","article-title":"Scrotal Histoplasmosis masquerading as Fournier's gangrene","volume":"25","author":"Sachdev","year":"2017","journal-title":"Int J Surg Pathol."},{"key":"2020062509434447300_ref8","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1086\/313904","article-title":"Two unusual presentations of urogenital histoplasmosis and a review of the literature","volume":"31","author":"Friskel","year":"2000","journal-title":"Clin Infect Dis."},{"key":"2020062509434447300_ref9","doi-asserted-by":"crossref","first-page":"ofz534","DOI":"10.1093\/ofid\/ofz534","article-title":"The diagnostic laboratory hub: a new health care system reveals the incidence and mortality of tuberculosis, Histoplasmosis, and Cryptococcosis of PWH in Guatemala","volume":"7","author":"Samayoa","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"2020062509434447300_ref10","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.3201\/eid2411.180236","article-title":"African Histoplasmosis in HIV-negative patients, Kimpese, Democratic Republic of the Congo","volume":"24","author":"Pakasa","year":"2018","journal-title":"Emerg Infect Dis."}],"container-title":["Oxford Medical Case 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