{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T18:52:08Z","timestamp":1767034328841,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,9,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>The rare cheiro-oral-pedal syndrome (COPS) is characterized by sensory disturbances around the corner of the mouth, and in the hand and foot of the same side. The causative lesion is located in the thalamocortical projections, thalamus or brainstem and is usually due to ischemic or hemorrhagic stroke. We report a case of a patient with brain stem cavernous malformations presented as pure COPS with additional sensory disturbance in the thorax. We report this case to raise awareness of these very rare syndromes and demonstrate that mildly presenting symptoms can be caused by an underlying devastating condition.<\/jats:p>","DOI":"10.1093\/omcr\/omaa074","type":"journal-article","created":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T13:24:50Z","timestamp":1600781090000},"source":"Crossref","is-referenced-by-count":2,"title":["Cheiro-oral-pedal syndrome as the presenting symptom of brainstem cavernous malformation: a case report"],"prefix":"10.1093","volume":"2020","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8676-5327","authenticated-orcid":false,"given":"Chumpol","family":"Anamnart","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Prapokklao Hospital, Chulalongkorn University, Chanthaburi, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siriwan","family":"Piyapittayanan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,9,22]]},"reference":[{"key":"2020092209244302800_ref1","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1010\/WNL.0000000000002701","article-title":"Natural history of cavernous malformation: systematic review and meta-analysis of 25 studies","volume":"86","author":"Taslimi","year":"2016","journal-title":"Neurology"},{"key":"2020092209244302800_ref2","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1161\/STROKEAHA.117.017074","article-title":"Cranial cavernous malformations: natural history and treatment","volume":"49","author":"Stapleton","year":"2018","journal-title":"Stroke"},{"key":"2020092209244302800_ref3","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1227\/01.NEU.0000335158.11692.53","article-title":"Symptomatic brainstem cavernomas","volume":"64","author":"Hauck","year":"2009","journal-title":"Neurosurgery"},{"key":"2020092209244302800_ref4","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000116803","article-title":"Cheiro-oral-pedal syndrome","volume":"32","author":"Yasuda","year":"1992","journal-title":"Eur Neurol"},{"key":"2020092209244302800_ref5","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S0022-510X(97)00173-1","article-title":"Unusual sensory disturbance in the thoracic region after stroke relationship to cheiro-oral and cheiro-oral-pedal syndrome","volume":"153","author":"Yaduda","year":"1997","journal-title":"J Neurol Sci"},{"key":"2020092209244302800_ref6","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.clineuro.2005.02.008","article-title":"Cheiro-oral-pedal syndrome due to brainstem hemorrhage","volume":"108","author":"Igarashi","year":"2016","journal-title":"Clin Neurol Neurosurg"},{"key":"2020092209244302800_ref7","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/S1474-4422(15)00303-8","article-title":"Clinical course of untreated cerebral cavernous malformations: a meta-analysis of individual patient data","volume":"15","author":"Horne","year":"2016","journal-title":"Lancet Neurol"},{"volume-title":"Cavernous Venous Malformation","year":"2020","author":"Zyck","key":"2020092209244302800_ref8"},{"key":"2020092209244302800_ref9","doi-asserted-by":"publisher","first-page":"2964","DOI":"10.1161\/STROKEAHA.119.026120","article-title":"Outcomes of surgery for brainstem cavernous malformations: a systematic review","volume":"50","author":"Kearns","year":"2019","journal-title":"Stroke"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2020\/9\/omaa074\/33778471\/omaa074.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2020\/9\/omaa074\/33778471\/omaa074.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T13:24:53Z","timestamp":1600781093000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaa074\/5909764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,1]]},"references-count":9,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaa074","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2020,9]]},"published":{"date-parts":[[2020,9,1]]},"article-number":"omaa074"}}