{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T08:23:41Z","timestamp":1776759821723,"version":"3.51.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Leiomyoma is a smooth muscle tumour that can arise in any part of the body especially the uterus. Even though it is traditionally linked with hormonal influence, it can also develop in extrauterine organs with a slight female predominance. It is indistinguishable with gastrointestinal stromal tumour (GIST) histologically. We report a case of a 30-year-old gentleman who presented with a huge painful mass in the right iliac fossa. Computed tomography revealed a 10\u2009\u00d7\u200910 cm homogeneous mass arising from the terminal ileum; he subsequently underwent an open right hemicolectomy. Histology showed a well-circumscribed lesion composed of interlacing bundles of smooth muscle fibres of the submucosa with positive smooth muscle actin and H-Caldesmon stains but negative for DOG-1 and CD117 (c-kit) stains which were consistent with leiomyoma. Despite its rarity, this hormone-related tumour needs to be considered regardless of gender. Immunohistochemistry is paramount as it is histologically identical to GIST.<\/jats:p>","DOI":"10.1093\/omcr\/omaa086","type":"journal-article","created":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T12:51:42Z","timestamp":1603457502000},"source":"Crossref","is-referenced-by-count":2,"title":["An oncological curiosity of a male patient with a huge leiomyoma of the terminal ileum"],"prefix":"10.1093","volume":"2020","author":[{"given":"Syaza","family":"Zainudin","sequence":"first","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saravana Kumar","family":"Rajanthran","sequence":"additional","affiliation":[{"name":"Department of Surgery, Queen Elizabeth Hospital, Ministry of Health Malaysia, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nornazirah","family":"Azizan","sequence":"additional","affiliation":[{"name":"Department of Pathobiology and Medical Diagnostic, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3757-9744","authenticated-orcid":false,"given":"Firdaus","family":"Hayati","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joriana","family":"Ginawoi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khairunnisa Aini","family":"Suhaimi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan Yee Lilian","family":"Voo","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohd Fazri","family":"Kiram","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Izzuddin","family":"Md Jaki","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siti Haja","family":"Abd Aziz","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subashini Thevi Nach","family":"Nacathiran","sequence":"additional","affiliation":[{"name":"Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,10,23]]},"reference":[{"key":"2020102308503684800_ref1","volume-title":"Robbins Basic Pathology E-Book","author":"Kumar","year":"2018","edition":"10th"},{"key":"2020102308503684800_ref2","first-page":"15977","article-title":"Superficial leiomyomas of the gastrointestinal tract with interstitial cells of Cajal","volume":"8","author":"Janevska","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"2020102308503684800_ref3","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1038\/s41379-020-0492-5","article-title":"Smooth muscle tumors of the gastrointestinal tract: an analysis of prognostic features in 407 cases","volume":"33","author":"Alpert","year":"2020","journal-title":"Modern Pathol"},{"key":"2020102308503684800_ref4","doi-asserted-by":"crossref","first-page":"3311","DOI":"10.3748\/wjg.v13.i24.3311","article-title":"Classification of submucosal tumors in the gastrointestinal tract","volume":"13","author":"Ponsaing","year":"2007","journal-title":"World J Gastroenterol"},{"key":"2020102308503684800_ref5","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s002689910067","article-title":"Tumors of the small intestine","volume":"24","author":"Blanchard","year":"2000","journal-title":"World J 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