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Chest x-ray on admission showed severe diffuse bilateral pulmonary infiltrates concerning for COVID-19 pneumonia. Electrocardiogram showed inferior and lateral ST-segment elevation compatible with acute inferolateral myocardial infarction. Successful percutaneous coronary intervention (PCI) of the proximal and mid-right coronary artery using the balloon angioplasty and drug-eluting stent was performed. Post-PCI stenosis was 0% with a thrombolysis in myocardial infarction (TIMI) flow of 3. Five-day course of azithromycin and hydroxychloroquine was completed with no improvement overall. Patient received two doses of 400\u00a0mg of tocilizumab intravenously on hospital days 5 (HD#5) and #6. The patient was proned, on FiO2 100%, PEEP 15\u00a0cm H2O, on epoprostenol sodium and paralytics and eventually received venovenous ECMO, which improved outcome.<\/jats:p>","DOI":"10.1093\/omcr\/omaa148","type":"journal-article","created":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T06:30:38Z","timestamp":1615444238000},"source":"Crossref","is-referenced-by-count":0,"title":["STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1106-3619","authenticated-orcid":false,"given":"Tanvir","family":"Rahman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quazim A","family":"Alayo","sequence":"additional","affiliation":[{"name":"St. Luke\u2019s Hospital, Chesterfield, MO, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sibgha 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