{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:36:53Z","timestamp":1777581413371,"version":"3.51.4"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T00:00:00Z","timestamp":1619654400000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Lymphoma of bone is a rare neoplasm composed of malignant lymphoid cells, producing a tumefactive lesion within bone. We report a 13-year-old male who presented with progressively increasing swellings at the right shoulder and right mid-thigh for one month. Radiological images revealed lytic destructive lesions associated with soft tissue masses in both sites and a pathological fracture on the right humerus. The patient had no significant medical history. Histological, immunohistochemical and fluorescent in-situ hybridization assessment of biopsies from the lesions confirmed the diagnosis of primary non-Hodgkin lymphoma of bone. Unfortunately, due to coronavirus disease 2019 outbreak, the patient was unable to follow-up treatment and died shortly after establishment of the diagnosis. Delay in diagnosis and treatment is of serious concern when it comes to improve the prognosis of patients with this disease.<\/jats:p>","DOI":"10.1093\/omcr\/omab024","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T08:16:33Z","timestamp":1619684193000},"source":"Crossref","is-referenced-by-count":2,"title":["Non-Hodgkin lymphoma of bone of the femur and humerus: a case report and review of the literature"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7226-0168","authenticated-orcid":false,"given":"Alex","family":"Mremi","sequence":"first","affiliation":[{"name":"Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania"},{"name":"Faculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremia J","family":"Pyuza","sequence":"additional","affiliation":[{"name":"Department of Pathology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania"},{"name":"Faculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5373-2000","authenticated-orcid":false,"given":"Bilal","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kilimanjaro Christian Medical Centre, Moshi, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice A","family":"Andongolile","sequence":"additional","affiliation":[{"name":"Kilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre, Moshi, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adnan","family":"Sadiq","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania"},{"name":"Department of Radiology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3647-5262","authenticated-orcid":false,"given":"James J","family":"Yahaya","sequence":"additional","affiliation":[{"name":"Department of Biomedical Science, College of Health Sciences, The University of Dodoma, Dodoma, Tanzania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1228-4245","authenticated-orcid":false,"given":"Karoly","family":"Szuhai","sequence":"additional","affiliation":[{"name":"Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pancras C W","family":"Hogendoorn","sequence":"additional","affiliation":[{"name":"Department of Pathology, Leiden University Medical Center, Leiden, The 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