{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:13:31Z","timestamp":1753877611148,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T00:00:00Z","timestamp":1629072000000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,8,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Dysautonomia is a dysfunction of the autonomic nervous system, which mediates both sympathetic and parasympathetic functions of the human body. Alcohol has been established to affect the autonomic function through liver injury and accumulation of vasodilators. Alcohol can induce peripheral neurological diseases as well. This case report describes a patient who had a chronic history of alcoholism and uncontrolled diabetes mellitus presenting for orthostatic hypotension and peripheral neuropathy without underlying liver disease or other endocrinopathies. Although diabetes mellitus was controlled pharmacologically and risk factors for orthostatic hypotension were managed conservatively, his symptoms did not improve which indicated an alcohol-related autonomic dysfunction, shedding light on one of long-term complications of alcoholism.<\/jats:p>","DOI":"10.1093\/omcr\/omab072","type":"journal-article","created":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T11:15:38Z","timestamp":1629112538000},"source":"Crossref","is-referenced-by-count":1,"title":["I drank too much and now I can\u2019t walk: a case of alcohol-induced dysautonomia"],"prefix":"10.1093","volume":"2021","author":[{"given":"Richard","family":"Assaker","sequence":"first","affiliation":[{"name":"St. Vincent\u2019s Medical Center, Bridgeport, CT, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2571-1450","authenticated-orcid":false,"given":"Georges","family":"El Hasbani","sequence":"additional","affiliation":[{"name":"American University of Beirut Medical Center, Beirut, Lebanon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arturo Alvarez","family":"Antezana","sequence":"additional","affiliation":[{"name":"Lincoln Medical and Mental Health Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Vargas","family":"Gamarra","sequence":"additional","affiliation":[{"name":"St. Vincent\u2019s Medical Center, Bridgeport, CT, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Amaya-Suarez","sequence":"additional","affiliation":[{"name":"Lincoln Medical and Mental Health Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Bertely","sequence":"additional","affiliation":[{"name":"Lincoln Medical and Mental Health Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Suleman","sequence":"additional","affiliation":[{"name":"Lincoln Medical and Mental Health Center, Bronx, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,8,13]]},"reference":[{"key":"2021081611104790700_ref1","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/S0025-6196(12)62272-1","article-title":"The central autonomic network: functional organization, dysfunction, and perspective","volume":"68","author":"Benarroch","year":"1993","journal-title":"Mayo Clin Proc"},{"key":"2021081611104790700_ref2","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1478-3231.2009.01985.x","article-title":"Autonomic dysfunction in chronic liver disease","volume":"29","author":"Frith","year":"2009","journal-title":"Liver Int"},{"key":"2021081611104790700_ref3","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0022-0736(78)80120-4","article-title":"Electrophysiologic properties of alcohol in man","volume":"11","author":"Gould","year":"1978","journal-title":"J Electrocardiol"},{"key":"2021081611104790700_ref4","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1001\/archneur.1995.00540250049012","article-title":"Autonomic and peripheral neuropathies in patients with chronic alcoholism. A dose-related toxic effect of alcohol","volume":"52","author":"Monforte","year":"1995","journal-title":"Arch Neurol"},{"key":"2021081611104790700_ref5","first-page":"69","article-title":"Autonomic dysfunction in long-standing alcoholism","volume":"21","author":"Matikainen","year":"1986","journal-title":"Alcohol Alcohol Oxf Oxfs"},{"key":"2021081611104790700_ref6","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3949\/ccjm.76a.08070","article-title":"Small fiber neuropathy: a burning problem","volume":"76","author":"Tavee","year":"2009","journal-title":"Cleve Clin J Med"},{"key":"2021081611104790700_ref7","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/mus.21946","article-title":"Alcohol-related peripheral neuropathy: nutritional, toxic, or both?","volume":"43","author":"Mellion","year":"2011","journal-title":"Muscle Nerve"},{"key":"2021081611104790700_ref8","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/ana.410020203","article-title":"Alcoholic neuropathy: clinical, electrophysiological, and biopsy findings","volume":"2","author":"Behse","year":"1977","journal-title":"Ann Neurol"},{"key":"2021081611104790700_ref9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/ana.10550","article-title":"Alcoholic neuropathy is clinicopathologically distinct from thiamine-deficiency neuropathy","volume":"54","author":"Koike","year":"2003","journal-title":"Ann Neurol"},{"key":"2021081611104790700_ref10","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1093\/alcalc\/agl058","article-title":"Treatment of alcoholic polyneuropathy with vitamin b complex: a randomized controlled trial","volume":"41","author":"Peters","year":"2006","journal-title":"Alcohol Alcohol"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2021\/8\/omab072\/39718042\/omab072.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2021\/8\/omab072\/39718042\/omab072.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,16]],"date-time":"2021-08-16T11:15:50Z","timestamp":1629112550000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omab072\/6350614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,1]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omab072","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2021,8]]},"published":{"date-parts":[[2021,8,1]]},"article-number":"omab072"}}