{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:14:39Z","timestamp":1753877679937,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"11-12","license":[{"start":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T00:00:00Z","timestamp":1637884800000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Sepsis has a high mortality rate; thus, in the intensive care unit, early diagnosis and adjunctive treatments are crucial. However, generally, most patients with sepsis from rural area initially visit the emergency department at a rural hospital and are managed in general medical wards in Japan. Here we report on an 81-year-old Japanese female manifesting septic shock caused by the upper urinary tract infection of extended-spectrum beta-lactamase-producing Escherichia coli secondary to the left ureter obstruction by the urothelial carcinoma. Broad-spectrum antibiotics were administered. Although critical for the source control of infection, drainage of the ureteropelvic junction could not be performed immediately because of catecholamine-resistant hypotension. Hence, we administered polymyxin B-immobilized fiber column direct hemoperfusion, followed by low-dose hydrocortisone administration. After 8\u00a0hours of infusion, she recovered from the septic shock and successfully underwent emergency percutaneous nephrostomy. This presented strategy may provide a new resolution of catecholamine-resistant patients in urosepsis.<\/jats:p>","DOI":"10.1093\/omcr\/omab109","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T10:42:41Z","timestamp":1638355361000},"source":"Crossref","is-referenced-by-count":0,"title":["Polymyxin B and low-dose hydrocortisone treatment in a patient with uroseptic shock in a rural health unit"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8198-0706","authenticated-orcid":false,"given":"Toshio","family":"Arai","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Furano Kyokai Hospital, Hokkaido, Japan"},{"name":"Department of Parasitology, National Institute of Infectious Disease, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichiro","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Furano Kyokai Hospital, Hokkaido, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saori","family":"Yoshizaki","sequence":"additional","affiliation":[{"name":"General Education Center, Kyorin University Hospital, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Ando","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Teine Keijin-Kai Hospital, Hokkaido, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunsuke","family":"Natori","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Furano Kyokai Hospital, Hokkaido, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shun","family":"Morishita","sequence":"additional","affiliation":[{"name":"Department of Urology, Furano Kyokai Hospital, Hokkaido, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyu","family":"Otani","sequence":"additional","affiliation":[{"name":"Department of Urology, Furano Kyokai Hospital, Hokkaido, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Numata","sequence":"additional","affiliation":[{"name":"Department of Urology, Furano Kyokai Hospital, Hokkaido, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Osanai","sequence":"additional","affiliation":[{"name":"Department of Urology, Furano Kyokai Hospital, Hokkaido, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"key":"2021122815202276000_ref1","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.euf.2018.11.003","article-title":"Management of urosepsis in 2018","volume":"5","author":"Bonkat","year":"2019","journal-title":"Eur Urol Focus."},{"key":"2021122815202276000_ref2","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/MAJ.0b013e3180a5e8d8","article-title":"Polymyxin B-immobilized fiber hemoperfusion with the PMX-05R column in elderly patients suffering from septic shock","volume":"334","author":"Nakamura","year":"2007","journal-title":"Am J Med Sci."},{"key":"2021122815202276000_ref3","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1001\/jama.2009.856","article-title":"Early use of polymyxin B hemoperfusion in abdominal septic shock: The EUPHAS randomized controlled trial","volume":"301","author":"Cruz","year":"2009","journal-title":"JAMA - J Am Med Assoc."},{"key":"2021122815202276000_ref4","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1007\/s00134-015-3751-z","article-title":"Early use of polymyxin B hemoperfusion in patients with septic shock due to peritonitis: a multicenter randomized control trial","volume":"41","author":"Payen","year":"2015","journal-title":"Intensive Care Med."},{"key":"2021122815202276000_ref5","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1007\/s00134-018-5463-7","article-title":"Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial","volume":"44","author":"Klein","year":"2018","journal-title":"Intensive Care Med."},{"key":"2021122815202276000_ref6","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1056\/NEJMoa1705835","article-title":"Adjunctive glucocorticoid therapy in patients with septic shock","volume":"378","author":"Venkatesh","year":"2018","journal-title":"N Engl J Med."},{"key":"2021122815202276000_ref7","doi-asserted-by":"crossref","first-page":"R21","DOI":"10.1186\/cc5696","article-title":"Effect of mode of hydrocortisone administration on glycemic control in patients with septic shock: a prospective randomized trial","volume":"11","author":"Loisa","year":"2007","journal-title":"Crit Care."},{"key":"2021122815202276000_ref8","doi-asserted-by":"crossref","first-page":"292","DOI":"10.9738\/INTSURG-D-13-00256.1","article-title":"The prone position during surgery and its complications: a systematic review and evidence-based guidelines","volume":"100","author":"Kwee","year":"2015","journal-title":"Int Surg."},{"key":"2021122815202276000_ref9","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1097\/MCC.0000000000000418","article-title":"Norepinephrine in septic shock: when and how much?","volume":"23","author":"Hamzaoui","year":"2017","journal-title":"Curr Opin Crit Care."},{"key":"2021122815202276000_ref10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/CCM.0000000000002026","article-title":"Rural patients with severe sepsis or septic shock who bypass rural hospitals have increased mortality: an instrumental variables approach","volume":"45","author":"Mohr","year":"2017","journal-title":"Crit Care Med."}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2021\/11-12\/omab109\/41940667\/omab109.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2021\/11-12\/omab109\/41940667\/omab109.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T15:55:25Z","timestamp":1640706925000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omab109\/6439717"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,1]]},"references-count":10,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2021,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omab109","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2021,11]]},"published":{"date-parts":[[2021,11,1]]},"article-number":"omab109"}}