{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T05:23:39Z","timestamp":1761110619870,"version":"3.41.2"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"11-12","license":[{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"vor","delay-in-days":57,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>We report a case of membranous conjunctivitis and erythema multiforme major (EMM) after a coronavirus disease 2019 (COVID-19) diagnosis. A previously well 18-year-old man presented with increasingly erythematous eyes and oral and genital ulceration 2\u00a0weeks after confirmation of COVID-19 infection. Clinical examination showed sloughy membranous conjunctivitis with normal visual acuity. He was reviewed by dermatology and diagnosed with EMM secondary to severe acute respiratory syndrome coronavirus 2 infection. The symptoms resolved with oral and topical steroids, lubricants and chloramphenicol eye drops. Erythema multiforme has been reported in association with COVID-19, although the major form is rare. Ophthalmologists should consider current or previous COVID-19 infection in patients presenting with conjunctivitis or pseudomembrane formation. Prompt initiation of steroids aids resolution.<\/jats:p>","DOI":"10.1093\/omcr\/omab120","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T15:51:13Z","timestamp":1640706673000},"source":"Crossref","is-referenced-by-count":4,"title":["Erythema multiforme major with ocular involvement following COVID-19 infection"],"prefix":"10.1093","volume":"2021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1410-2150","authenticated-orcid":false,"given":"Carla L","family":"Maden","sequence":"first","affiliation":[{"name":"FY2, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Ah-Kye","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Royal Free London NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasmin","family":"Alfallouji","sequence":"additional","affiliation":[{"name":"Dermatology Department, University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Kulakov","sequence":"additional","affiliation":[{"name":"Dermatology Department, University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Ellery","sequence":"additional","affiliation":[{"name":"Histopathology Department, University College London Hospitals NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5656-6749","authenticated-orcid":false,"given":"Esther","family":"Papamichael","sequence":"additional","affiliation":[{"name":"Ophthalmology Department, Royal Free London NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,12,28]]},"reference":[{"key":"2021122815193052100_ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000512932","article-title":"Skin manifestations associated with COVID-19: current knowledge and future perspectives","volume":"237","author":"Genovese","year":"2021","journal-title":"Dermatology"},{"key":"2021122815193052100_ref2","first-page":"103","article-title":"Ocular manifestations of COVID-19: a systematic review and meta-analysis","volume":"16","author":"Nasiri","year":"2021","journal-title":"J Ophthalmic Vis Res"},{"key":"2021122815193052100_ref3","first-page":"642","article-title":"Erythema multiforme and related disorders. Oral Surg. Oral Med. Oral Pathol. Oral Radiol","volume":"103","author":"Al-Johani","year":"2007","journal-title":"Endodontol."},{"key":"2021122815193052100_ref4","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1365-4632.2011.05348.x","article-title":"Clinical features, diagnosis, and treatment of erythema multiforme: a review for the practicing dermatologist","volume":"51","author":"Sokumbi","year":"2012","journal-title":"Int J Dermatol"},{"key":"2021122815193052100_ref5","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s40257-020-00558-4","article-title":"Cutaneous manifestations of COVID-19: an evidence-based review","volume":"21","author":"Daneshgaran","year":"2020","journal-title":"Am J Clin Dermatol"},{"key":"2021122815193052100_ref6","doi-asserted-by":"crossref","first-page":"e539","DOI":"10.1111\/jdv.16666","article-title":"Erythema multiforme and Kawasaki disease associated with COVID-19 infection in children","volume":"34","author":"Lab\u00e9","year":"2020","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2021122815193052100_ref7","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/ijd.15158","article-title":"A case of erythema multiforme major with multiple mucosal involvements in COVID-19 infection","volume":"60","author":"Binois","year":"2021","journal-title":"Int J Dermatol"},{"key":"2021122815193052100_ref8","doi-asserted-by":"crossref","first-page":"e236986","DOI":"10.1136\/bcr-2020-236986","article-title":"Special dermatological presentation of paediatric multisystem inflammatory syndrome related to COVID-19: erythema multiforme","volume":"13","author":"Bapst","year":"2020","journal-title":"BMJ Case Rep"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2021\/11-12\/omab120\/41940683\/omab120.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2021\/11-12\/omab120\/41940683\/omab120.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T15:51:24Z","timestamp":1640706684000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omab120\/6485139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,1]]},"references-count":8,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2021,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omab120","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2021,11]]},"published":{"date-parts":[[2021,11,1]]},"article-number":"omab120"}}