{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T03:12:02Z","timestamp":1779160322781,"version":"3.51.4"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T00:00:00Z","timestamp":1647561600000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>A 21-year-old male from Nepal, with a history of travel to Mumbai 2\u00a0months ago, presented with fever with chills and rigors, vomiting and multiple joint pain for 1\u00a0week. Clinical examination was noteworthy for tachycardia, hypotension and positive tourniquet test. Lab reports showed NS1-Ag positive, thrombocytopenia, lymphocytosis, transaminesemia, hyperbilirubinemia, increased urea and creatinine. He was treated for severe dengue. His laboratory parameters started improving; however, he had fever with chills and rigors daily and persistent vomiting. Repeat peripheral smear for Malaria showed schizonts and trophozoites of Plasmodium vivax. He recovered following treatment with IV fluids and injection artesunate. The presence of fever even in a critical phase of dengue, the typical rise of temperature daily, and jaundice gave a clue of coinfection with Malaria. On follow-up, after 2\u00a0weeks, he had no symptoms, and all the laboratory parameters were normal.<\/jats:p>","DOI":"10.1093\/omcr\/omac022","type":"journal-article","created":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T11:35:31Z","timestamp":1647603331000},"source":"Crossref","is-referenced-by-count":11,"title":["Dengue and malaria coinfection: the first case report in Nepal"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5588-4902","authenticated-orcid":false,"given":"Arun","family":"Gautam","sequence":"first","affiliation":[{"name":"Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6524-5525","authenticated-orcid":false,"given":"Ujjwal","family":"Aryal","sequence":"additional","affiliation":[{"name":"Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6027-3113","authenticated-orcid":false,"given":"Sudeep","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5124-6460","authenticated-orcid":false,"given":"Saugat","family":"Pradhan","sequence":"additional","affiliation":[{"name":"Microbiology, B.P. Koirala institute of Health sciences, Dharan 56700, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5895-1405","authenticated-orcid":false,"given":"Urza","family":"Bhattarai","sequence":"additional","affiliation":[{"name":"Geriatric Medicine, All India Institute of Medical Sciences, New Delhi 110029), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6618-3650","authenticated-orcid":false,"given":"Akshat","family":"Mishra","sequence":"additional","affiliation":[{"name":"Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8392-8028","authenticated-orcid":false,"given":"Sanjib Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Internal Medicine, B.P. Koirala Institute of Health Sciences, Dharan 56700, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,3,16]]},"reference":[{"key":"2022031811301849400_ref1","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S2221-1691(11)60053-1","article-title":"Concurrent malaria and dengue infection: a brief summary and comment","volume":"1","author":"Wiwanitkit","year":"2011","journal-title":"Asian Pac J Trop Biomed"},{"key":"2022031811301849400_ref2","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1590\/S0037-86822010000500007","article-title":"Concurrent dengue and malaria in the Amazon region","volume":"43","author":"Santana","year":"2010","journal-title":"Rev Soc Bras Med Trop"},{"key":"2022031811301849400_ref3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.apjtb.2016.05.008","article-title":"A review of concurrent infections of malaria and dengue in Asia","volume":"6","author":"Sahu","year":"2016","journal-title":"Asian Pac J Trop Biomed"},{"key":"2022031811301849400_ref4","volume-title":"Annual Report Department of Health Services 2076\/77 (2019\/20)","author":"Government of Nepal, Department of Health Services","year":"2020"},{"key":"2022031811301849400_ref5","article-title":"Assessment and initial management of acute undifferentiated fever in tropical and subtropical regions","volume":"363","author":"Bhargava","year":"2018","journal-title":"BMJ"},{"key":"2022031811301849400_ref6","doi-asserted-by":"crossref","first-page":"e0253556","DOI":"10.1371\/journal.pone.0253556","article-title":"Malaria and dengue in Hodeidah city, Yemen: high proportion of febrile outpatients with dengue or malaria, but low proportion co-infected","volume":"16","author":"Abdul-Ghani","year":"2021","journal-title":"PLoS One"},{"key":"2022031811301849400_ref7","doi-asserted-by":"crossref","first-page":"e3239","DOI":"10.1371\/journal.pntd.0003239","article-title":"P. vivax malaria and dengue fever co-infection: a cross-sectional study in the Brazilian Amazon","volume":"8","author":"Magalh\u00e3es","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"2022031811301849400_ref8","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/S1473-3099(13)70095-1","article-title":"The activation of vivax malaria hypnozoites by infectious diseases","volume":"13","author":"Shanks","year":"2013","journal-title":"Lancet Infect Dis"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2022\/3\/omac022\/42908880\/omac022.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2022\/3\/omac022\/42908880\/omac022.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,18]],"date-time":"2022-03-18T11:35:41Z","timestamp":1647603341000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omac022\/6549461"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,1]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omac022","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,3]]},"published":{"date-parts":[[2022,3,1]]},"article-number":"omac022"}}