{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T23:35:46Z","timestamp":1781566546821,"version":"3.54.5"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:00:00Z","timestamp":1656288000000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Heterotopic pancreas is a congenital anomaly defined as the presence of the pancreatic tissue outside its normal location, which is usually discovered incidentally. We describe a rare case of heterotopic pancreatic tissue in the neck and the node surrounding the cystic duct of the gallbladder. A 33-year-old female presented with right upper quadrant abdominal pain aggravated after fat meals. The diagnosis was made as chronic cholecystitis. Laparoscopic cholecystectomy was performed. Pathologic examination showed a lobulated nodule connected to the cystic duct. Microscopically, this node consisted of all components of pancreatic tissue. Localization of heterotopic pancreatic tissue in the gallbladder is exceedingly rare. Less than 40 cases of heterotopic pancreas in the gallbladder have been reported worldwide. The ectopic pancreas is an extraordinary congenital entity. Although pancreatic tissue in the lymph node is an exceptional finding, pathologists should be aware of it because it may be confused with tumor or metastasis.<\/jats:p>","DOI":"10.1093\/omcr\/omac068","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T10:38:03Z","timestamp":1656326283000},"source":"Crossref","is-referenced-by-count":4,"title":["Heterotopic pancreatic tissue in the gall bladder neck and lymph node surrounding cystic duct identified during cholecystectomy for chronic calculous cholecystitis: a rare case report from Syria"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1675-4125","authenticated-orcid":false,"given":"Moatasem Hussein","family":"Al-janabi","sequence":"first","affiliation":[{"name":"Department of Pathology , Cancer Research Center, Tishreen University Hospital, Lattakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leen","family":"Ismail","sequence":"additional","affiliation":[{"name":"Tishreen University Faculty of Medicine , Lattakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marah Yousef","family":"Wassouf","sequence":"additional","affiliation":[{"name":"Tishreen University Faculty of Medicine , Lattakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamal","family":"Sulaiman","sequence":"additional","affiliation":[{"name":"Department of General Surgery , Tishreen University Hospital, Lattakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabab","family":"Salloum","sequence":"additional","affiliation":[{"name":"Department of Pathology , Tishreen University Hospital, Lattakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuheir","family":"Al-shehabi","sequence":"additional","affiliation":[{"name":"Department of Pathology , Director of Cancer Research Center, Tishreen University Hospital, Lattakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,6,23]]},"reference":[{"key":"2022062710372415500_ref1","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1097\/MPA.0b013e31803816fc","article-title":"Heterotopic pancreas in the gallbladder. The importance of an uncommon condition","volume":"34","author":"Beltran","year":"2007","journal-title":"Pancreas"},{"key":"2022062710372415500_ref2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/BF00427004","article-title":"A case of heterotopic pancreas in lymph node","volume":"377","author":"Murayama","year":"1978","journal-title":"Virchows Arch A Pathol Anat Histol"},{"key":"2022062710372415500_ref3","first-page":"464","article-title":"Pancreatic heterotopia in the gallbladder associated with chronic cholecystitis: a rare combination","volume":"11","author":"Al-Shraim","year":"2010","journal-title":"JOP"},{"key":"2022062710372415500_ref4","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.yexmp.2003.08.005","article-title":"Islet cell tumor arising from a heterotopic pancreas in the duodenal wall with ulceration","volume":"76","author":"Tolentino","year":"2004","journal-title":"Exp Mol Pathol"},{"key":"2022062710372415500_ref5","doi-asserted-by":"crossref","first-page":"250","DOI":"10.5455\/aces.20151012123519","article-title":"Heterotopic pancreatic tissue in the gallbladder","volume":"5","author":"Marcano","year":"2016","journal-title":"Arch Clin Exp Surg"},{"key":"2022062710372415500_ref6","doi-asserted-by":"crossref","first-page":"834","DOI":"10.15537\/smj.2018.8.22602","article-title":"Heterotopic pancreatic tissue in the gallbladder","volume":"39","author":"Sharma","year":"2018","journal-title":"Saudi Med J"},{"key":"2022062710372415500_ref7","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1186\/1757-1626-1-249","article-title":"Carcinoma developing in ectopic pancreatic tissue in the stomach: a case report","volume":"1","author":"Papaziogas","year":"2008","journal-title":"Cases J"},{"key":"2022062710372415500_ref8","doi-asserted-by":"crossref","first-page":"bcr2016218804","DOI":"10.1136\/bcr-2016-218804","article-title":"Primary tuberculosis of cystic duct lymph node","volume":"2017","author":"Ghazanfar","year":"2017","journal-title":"BMJ Case Rep"},{"key":"2022062710372415500_ref9","doi-asserted-by":"crossref","first-page":"142","DOI":"10.4103\/2229-516X.106360","article-title":"Heterotopic pancreas in gall bladder associated with chronic cholecystolithiasis","volume":"2","author":"Elhence","year":"2012","journal-title":"Int J Appl Basic Med Res"},{"key":"2022062710372415500_ref10","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1272\/jnms.74.168","article-title":"A case of intra-abdominal endocrine tumor possibly arising from an ectopic pancreas","volume":"74","author":"Ogata","year":"2007","journal-title":"J Nippon Med Sch"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2022\/6\/omac068\/44221885\/omac068.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2022\/6\/omac068\/44221885\/omac068.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T10:38:12Z","timestamp":1656326292000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omac068\/6614597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,1]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omac068","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,6]]},"published":{"date-parts":[[2022,6,1]]},"article-number":"omac068"}}