{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T16:17:35Z","timestamp":1764260255491,"version":"3.41.2"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T00:00:00Z","timestamp":1669334400000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Nail psoriasis causes significant aesthetic and functional disabilities. The treatment of nail psoriasis is essential to improve the health outcomes and quality of life among patients. Pain associated with intralesional injections, inadequate penetration into the nail and underlying tissue, poor adherence to therapy, limited efficacy and recurrent relapses are among the many challenging issues with topical therapy. While conventional systemic therapies are still useful and often appropriate for some patients, current evidence indicates that highly selective agents including anti-tumor necrosis factor-alpha, anti-interleukin (IL)-17 and anti-IL-12\/23 antibodies that are primarily available for plaque psoriasis and psoriatic arthritis have also demonstrated long-term efficacy in the treatment of nail psoriasis. We report a case of nail psoriasis improved with treatment by risankizumab.<\/jats:p>","DOI":"10.1093\/omcr\/omac127","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T12:19:53Z","timestamp":1669378793000},"source":"Crossref","is-referenced-by-count":5,"title":["A case of nail psoriasis improved with treatment by risankizumab"],"prefix":"10.1093","volume":"2022","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4671-010X","authenticated-orcid":false,"given":"Abdulmajeed","family":"AlAjlan","sequence":"first","affiliation":[{"name":"King Saud University, King Saud University Medical City Dermatology Department, , Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0951-3438","authenticated-orcid":false,"given":"Raghda","family":"Qasim","sequence":"additional","affiliation":[{"name":"Dammam Medical Complex, Dammam Dermatology Department, , Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2207-5703","authenticated-orcid":false,"given":"Fatimah","family":"AlTassan","sequence":"additional","affiliation":[{"name":"King Saud University College of Medicine, , Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6178-0579","authenticated-orcid":false,"given":"Tala","family":"Qadoumi","sequence":"additional","affiliation":[{"name":"King Saud University, King Saud University Medical City Dermatology Department, , Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6921-1103","authenticated-orcid":false,"given":"Tuqa","family":"AlKaff","sequence":"additional","affiliation":[{"name":"King Saud University, King Saud University Medical City Dermatology Department, , Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,11,24]]},"reference":[{"key":"2022112510403443200_ref1","doi-asserted-by":"crossref","first-page":"83","DOI":"10.2147\/PTT.S165943","article-title":"Spotlight on risankizumab and its potential in the treatment of plaque psoriasis: evidence to date","volume":"8","author":"Machado","year":"2018","journal-title":"Psoriasis Targets Ther"},{"key":"2022112510403443200_ref2","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.3390\/ijms20061475","article-title":"Psoriasis pathogenesis and treatment","volume":"20","author":"Rendon","year":"2019","journal-title":"Int J Mol Sci"},{"key":"2022112510403443200_ref3","first-page":"51","article-title":"Nail psoriasis: clinical features, pathogenesis, differential diagnoses, and management","volume":"7","author":"Haneke","year":"2017","journal-title":"Journal of psoriasis"},{"key":"2022112510403443200_ref4","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1590\/abd1806-4841.20142633","article-title":"Nail psoriasis: a review of the literature","volume":"89","author":"Schons","year":"2014","journal-title":"An Bras Dermatol"},{"key":"2022112510403443200_ref5","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1007\/s40265-016-0564-5","article-title":"Nail psoriasis: a review of treatment options","volume":"76","author":"Pasch","year":"2016","journal-title":"Drugs"},{"volume-title":"Skyrizi\u00ae (risankizumab-rzaa) injection, for subcutaneous use: US prescribing information","year":"2019","author":"AbbVie","key":"2022112510403443200_ref6"},{"key":"2022112510403443200_ref7","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1007\/s13555-021-00523-x","article-title":"Nail psoriasis: a review of effective therapies and recommendations for management","volume":"11","author":"Hadeler","year":"2021","journal-title":"Dermatol Ther (Heidelb)"},{"key":"2022112510403443200_ref8","doi-asserted-by":"crossref","first-page":"7873","DOI":"10.3390\/ijms21217873","article-title":"Paradoxical psoriasis induced by anti-TNF\u03b1 treatment: evaluation of disease-specific clinical and genetic markers","volume":"21","author":"Bucalo","year":"2020","journal-title":"Int J Mol Sci"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2022\/11\/omac127\/47256149\/omac127.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2022\/11\/omac127\/47256149\/omac127.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T12:20:00Z","timestamp":1669378800000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omac127\/6845484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,1]]},"references-count":8,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omac127","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2022,11]]},"published":{"date-parts":[[2022,11,1]]},"article-number":"omac127"}}