{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:32:02Z","timestamp":1768005122956,"version":"3.49.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:00:00Z","timestamp":1685404800000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This case report explores a 34-year-old male diagnosed with mesothelioma who had no known risk factors. The patient initially was treated for empyema with antibiotics but later represented to hospital with worsening symptoms. He underwent a surgical Video-assisted thoracoscopic surgery procedure and lung biopsy, which revealed a diagnosis of mesothelioma. The young age of the patient as well as absence of significant risk factors for mesothelioma made the diagnosis unexpected. The patient had total body irradiation (TBI) therapy for leukaemia as a child, which increases the risk of developing cancer. However, there are limited studies exploring the risk of pleural mesothelioma post-TBI. Young patients who represent to hospital, with limited response to initial treatment, and suspicious radiological features should be considered for lung biopsy to reduce the risk of a missed diagnosis. Patients with a background of TBI should also be considered for follow-up to monitor for any subsequent malignancy.<\/jats:p>","DOI":"10.1093\/omcr\/omac151","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T11:47:18Z","timestamp":1685447238000},"source":"Crossref","is-referenced-by-count":2,"title":["A case of malignant mesothelioma in a young patient with childhood leukaemia who had received total body irradiation"],"prefix":"10.1093","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-7496","authenticated-orcid":false,"given":"Redwan","family":"Hayat","sequence":"first","affiliation":[{"name":"General Practice, Broomfield Hospital , Chelmsford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9829-2758","authenticated-orcid":false,"given":"Saad","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Acute Medicine, Colchester General Hospital , Colchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rekha","family":"Badiger","sequence":"additional","affiliation":[{"name":"Respiratory Medicine, Colchester General Hospital , Colchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi Han","family":"Lee","sequence":"additional","affiliation":[{"name":"Respiratory Medicine, Colchester General Hospital , Colchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Peryt","sequence":"additional","affiliation":[{"name":"Cardiothoracic Surgery, Royal Papworth Hospital , Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Gilligan","sequence":"additional","affiliation":[{"name":"Cambridge University Hospitals Clinical Oncology, , Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zubair","family":"Khalid","sequence":"additional","affiliation":[{"name":"Respiratory Medicine, Broomfield Hospital 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cervix","volume":"116","author":"Boice","year":"1988","journal-title":"Radiat Res"},{"key":"2023053011454775800_ref8","article-title":"Total body irradiation in haematopoietic stem cell transplantation for paediatric acute lymphoblastic leukaemia: review of the literature and future directions","volume":"9","author":"Hoeben","year":"2021","journal-title":"Front Pediatr [Internet]"},{"key":"2023053011454775800_ref9","first-page":"138","article-title":"Metastatic peritoneal mesothelioma in a 21-year-old female with chronic myelogenous leukemia","author":"Gupta","year":"2014"},{"key":"2023053011454775800_ref10","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/pbc.21335","article-title":"The British childhood cancer survivor study: objectives, methods, population structure, response rates and initial descriptive information","volume":"50","author":"Hawkins","year":"2008","journal-title":"Pediatr Blood Cancer [Internet]"}],"container-title":["Oxford Medical Case 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