{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:30:58Z","timestamp":1787679058011,"version":"build-2784847793"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>We present a case of a 29-year-old immunocompetent female without any known comorbidities with intermittent headache and vomiting who was ultimately diagnosed with cryptococcal meningitis (CM). Though her neuroimaging findings were atypical to those commonly found in CM, she was diagnosed with CM with a cryptococcal antigen test. However, in contrast to the good prognosis as stated in the literature, she died during her course stay at the hospital. Therefore, cryptococcosis should be taken as differentials, even in an immunocompetent individual presenting with features suggestive of meningitis, to prevent the worst clinical outcome.<\/jats:p>","DOI":"10.1093\/omcr\/omad016","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T09:15:41Z","timestamp":1679908541000},"source":"Crossref","is-referenced-by-count":4,"title":["Neuro-cryptococcosis in an immunocompetent individual with radiologically atypical findings: a case report and review of literature"],"prefix":"10.1093","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9601-2457","authenticated-orcid":false,"given":"Binit U","family":"Regmi","sequence":"first","affiliation":[{"name":"Jibjibe Primary Health Care Center Department of Neurology, , Rasuwa, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0811-8316","authenticated-orcid":false,"given":"Bishnu D","family":"Pathak","sequence":"additional","affiliation":[{"name":"Jibjibe Primary Health Care Center Department of Neurology, , Rasuwa, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0144-2738","authenticated-orcid":false,"given":"Ram C","family":"Subedi","sequence":"additional","affiliation":[{"name":"Grande International Hospital Department of Neurology, , Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9432-5233","authenticated-orcid":false,"given":"Bishal","family":"Dhakal","sequence":"additional","affiliation":[{"name":"Nepalese Army Institute of Health and Sciences Department of Neurology, , Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9310-0590","authenticated-orcid":false,"given":"Suhail","family":"Sapkota","sequence":"additional","affiliation":[{"name":"Nepalese Army Institute of Health and Sciences Department of Neurology, , Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5577-2601","authenticated-orcid":false,"given":"Sushil","family":"Joshi","sequence":"additional","affiliation":[{"name":"Dodhara Primary Health Care Center Department of Neurology, , Mahendranagar, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ujjawal","family":"Poudel","sequence":"additional","affiliation":[{"name":"Jibjibe Primary Health Care Center Department of Neurology, , Rasuwa, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raju","family":"Poudel","sequence":"additional","affiliation":[{"name":"Nepalese Army Institute of Health and Sciences Department of Neurology, , Kathmandu, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,3,25]]},"reference":[{"key":"2023032713153545500_","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s40475-015-0046-y","article-title":"Cryptococcal meningitis: diagnosis and management update","volume":"2","author":"Abassi","year":"2015","journal-title":"Curr Trop Med Rep"},{"key":"2023032713153545500_","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1016\/j.amjmed.2019.04.026","article-title":"Presentation and mortality of cryptococcal infection varies by predisposing illness: a retrospective cohort study","volume":"132","author":"Hevey","year":"2019","journal-title":"Am J Med"},{"key":"2023032713153545500_","first-page":"1","volume-title":"World Health Organization. Guidelines for the Diagnosis, Prevention and Management of Cryptococcal Disease","author":"WHO","year":"2018"},{"key":"2023032713153545500_","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1093\/cid\/ciaa1243","article-title":"Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living with human immunodeficiency virus: systematic review and meta-analysis of diagnostic test accuracy studies","volume":"72","author":"Temfack","year":"2021","journal-title":"Clin Infect Dis"},{"key":"2023032713153545500_","first-page":"61","article-title":"Cryptococcal infections in non-HIV-infected patients","volume":"124","author":"Pappas","year":"2013","journal-title":"Trans Am Clin Climatol Assoc"},{"key":"2023032713153545500_","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S1473-3099(17)30243-8","article-title":"Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis","volume":"17","author":"Rajasingham","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"2023032713153545500_","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/myc.12393","article-title":"Burden of serious fungal infections in Nepal","volume":"58","author":"Khwakhali","year":"2015","journal-title":"Mycoses"},{"key":"2023032713153545500_","doi-asserted-by":"crossref","first-page":"232470961983457","DOI":"10.1177\/2324709619834578","article-title":"Cryptococcal meningitis in an apparent immunocompetent patient","volume":"7","author":"Poley","year":"2019","journal-title":"J Investig Med High Impact Case Rep"},{"key":"2023032713153545500_","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/ccr3.4894","article-title":"Cryptococcal meningitis in an immunocompetent individual: a case report","volume":"9","author":"Acharya","year":"2021","journal-title":"Clin Case Reports"},{"key":"2023032713153545500_","first-page":"1","article-title":"Case report: Cryptococcal meningitis in an apparently immunocompetent patient in Nepal-challenges in diagnosis and treatment","volume":"4","author":"Jha","year":"2019","journal-title":"Wellcome Open Res"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2023\/3\/omad016\/49630800\/omad016.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2023\/3\/omad016\/49630800\/omad016.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T13:30:25Z","timestamp":1702128625000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omad016\/7085882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,1]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omad016","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,3]]},"published":{"date-parts":[[2023,3,1]]},"article-number":"omad016"}}