{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T03:01:43Z","timestamp":1769828503631,"version":"3.49.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T00:00:00Z","timestamp":1682035200000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Limited options are available for infertility associated with damaged or suboptimal tissues, typically the endometrium or ovaries. The goal of regenerative medicine is to restore function to specific tissues. Here, a 35-year-old female patient underwent two interventions of regenerative medicine: (i) autologous mesenchymal stem cells (MSCs) were applied in the myometrium, and (ii) intraovarian infusion of platelet-rich plasma (PRP). After two failed in vitro fertilization cycles (IVF), in which the endometrium was &amp;lt;5\u00a0mm, MSCs were applied, achieving a 7\u00a0mm trilaminar lining; however, the embryo quality remained poor. Therefore, intraovarian PRP was utilized for the next IVF cycle; the patient\u2019s response improved, and a euploid embryo developed. After the embryo transfer and a normal 38\u00a0weeks of pregnancy, a baby girl was born. Here, we demonstrate two forms of regenerative medicine that can be utilized to improve IVF.<\/jats:p>","DOI":"10.1093\/omcr\/omad037","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T13:09:22Z","timestamp":1682082562000},"source":"Crossref","is-referenced-by-count":2,"title":["Personalized regenerative strategies and molecular diagnosis for<i>in vitro<\/i>fertilization success: a case report"],"prefix":"10.1093","volume":"2023","author":[{"given":"Dinorah","family":"Hern\u00e1ndez-Melchor","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional (CINVESTAV-IPN) Science, Technology and Society Program, , M\u00e9xico City 07360, M\u00e9xico"},{"name":"Instituto Regenera SC , M\u00e9xico City 05320, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00e1n","family":"Madrazo","sequence":"additional","affiliation":[{"name":"Instituto de Infertilidad y Gen\u00e9tica M\u00e9xico SC, INGENES Investigaci\u00f3n Cl\u00ednica, , M\u00e9xico City 05320, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Am\u00e9rica","family":"Padilla-Viveros","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional (CINVESTAV-IPN) Science, Technology and Society Program, , M\u00e9xico City 07360, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Camargo","sequence":"additional","affiliation":[{"name":"Instituto de Infertilidad y Gen\u00e9tica M\u00e9xico SC, INGENES Investigaci\u00f3n Cl\u00ednica, , M\u00e9xico City 05320, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"L\u00f3pez-Bayghen","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n y de Estudios Avanzados del Instituto Polit\u00e9cnico Nacional (CINVESTAV-IPN) Departamento de Toxicolog\u00eda, , Av. IPN 2508 San Pedro Zac, CDMX 07360, M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,4,20]]},"reference":[{"key":"2023042113072397400_ref1","doi-asserted-by":"crossref","first-page":"367","DOI":"10.4103\/jomfp.JOMFP_93_18","article-title":"Stem-cell therapy and platelet-rich plasma in regenerative medicines: a review on pros and cons of the technologies","volume":"22","author":"Ramaswamy Reddy","year":"2018","journal-title":"J Oral Maxillofac Pathol"},{"key":"2023042113072397400_ref2","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.addr.2014.10.019","article-title":"Regenerative medicine for the treatment of reproductive system disorders: current and potential options","volume":"82-83","author":"Sadri-Ardekani","year":"2015","journal-title":"Adv Drug Deliv Rev"},{"key":"2023042113072397400_ref3","doi-asserted-by":"crossref","first-page":"553","DOI":"10.29252\/ijrm.14.9.553","article-title":"Reproductive biology, stem cells biotechnology and regenerative medicine: a 1-day national symposium held at Shahid Sadoughi University of Medical Sciences","volume":"14","author":"Akyash","year":"2016","journal-title":"Int J Reprod BioMed"},{"key":"2023042113072397400_ref4","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1093\/humrep\/deab106","article-title":"Intraovarian injection of platelet-rich plasma in assisted reproduction: too much too soon?","volume":"36","author":"Atkinson","year":"2021","journal-title":"Hum Reprod"},{"key":"2023042113072397400_ref5","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1016\/j.fertnstert.2021.12.025","article-title":"Optimal endometrial thickness in fresh and frozen-thaw in vitro fertilization cycles: an analysis of live birth rates from 96,000 autologous embryo transfers","volume":"117","author":"Mahutte","year":"2022","journal-title":"Fertil Steril"},{"key":"2023042113072397400_ref6","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2019.103078","article-title":"Intrauterine infusion of autologous platelet-rich plasma in women undergoing assisted reproduction: a systematic review and meta-analysis","volume":"137","author":"Maleki-Hajiagha","year":"2020","journal-title":"J Reprod Immunol"},{"key":"2023042113072397400_ref7","first-page":"062","volume-title":"Seminars in Reproductive Medicine: 2009","author":"Guzeloglu-Kayisli","year":"2009"},{"key":"2023042113072397400_ref8","doi-asserted-by":"crossref","first-page":"9071720","DOI":"10.1155\/2019\/9071720","article-title":"Using mesenchymal stem cells to treat female infertility: an update on female reproductive diseases","volume":"2019","author":"Zhao","year":"2019","journal-title":"Stem Cells Int"},{"key":"2023042113072397400_ref9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.bjps.2015.10.015","article-title":"Stromal vascular fraction: a regenerative reality? Part 1: current concepts and review of the literature","volume":"69","author":"Nguyen","year":"2016","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"2023042113072397400_ref10","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.stem.2008.08.008","article-title":"All MSCs are pericytes?","volume":"3","author":"Caplan","year":"2008","journal-title":"Cell Stem Cell"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2023\/4\/omad037\/50047773\/omad037.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2023\/4\/omad037\/50047773\/omad037.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T05:47:00Z","timestamp":1702273620000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omad037\/7133564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,1]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omad037","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,4]]},"published":{"date-parts":[[2023,4,1]]},"article-number":"omad037"}}