{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:04:34Z","timestamp":1753877074117,"version":"3.41.2"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T00:00:00Z","timestamp":1687737600000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Focal nodular hyperplasia (FNH) is the second most common intrahepatic benign mass lesion; however, extremely rarely, FNH grows in an exophytic manner. It is unclear whether pedunculated FNH can be managed in the same way as intrahepatic FNH. A 35-year-old female presented with right upper quadrant pain, and dynamic enhanced computed tomography revealed an exophytic hyperdense mass lesion originating from the liver, suggesting a pedunculated FNH. Shortly thereafter, she conceived. Since there was a history of acute abdomen, as well as the possibility of torsion of the mass or sudden massive bleeding during pregnancy, laparoscopic resection was performed at 17\u00a0weeks of gestation. Her postoperative and pregnancy course was uneventful, and she delivered a baby by cesarean section at 41\u00a0weeks of gestation. Our case suggests that pedunculated FNH, unlike typical intrahepatic FNH, may be better managed by laparoscopic surgery during pregnancy, resulting in favorable maternal and fetal outcomes.<\/jats:p>","DOI":"10.1093\/omcr\/omad054","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T17:32:33Z","timestamp":1687800753000},"source":"Crossref","is-referenced-by-count":3,"title":["Laparoscopic resection for pedunculated focal nodular hyperplasia of the liver during pregnancy"],"prefix":"10.1093","volume":"2023","author":[{"given":"Ai","family":"Akaguma","sequence":"first","affiliation":[{"name":"Graduate School of Medicine, Kyoto University Department of Gynecology and Obstetrics, , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takamichi","family":"Ishii","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Kyoto University Department of Surgery, , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoichiro","family":"Uchida","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Kyoto University Department of Surgery, , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9629-5912","authenticated-orcid":false,"given":"Yoshitsugu","family":"Chigusa","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Kyoto University Department of Gynecology and Obstetrics, , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Ueda","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Kyoto University Department of Gynecology and Obstetrics, , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Mandai","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Kyoto University Department of Gynecology and Obstetrics, , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruta","family":"Mogami","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine, Kyoto University Department of Gynecology and Obstetrics, , Kyoto, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,6,26]]},"reference":[{"key":"2023062616284859100_ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/pin.13186","article-title":"Liver pathology in pregnancy","volume":"72","author":"Birkness-Gartman","year":"2022","journal-title":"Pathol Int"},{"key":"2023062616284859100_ref2","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.amjsurg.2012.02.006","article-title":"Management of the focal nodular hyperplasia of the liver: evaluation of the surgical treatment comparing with observation only","volume":"204","author":"Perrakis","year":"2012","journal-title":"Am J Surg"},{"key":"2023062616284859100_ref3","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1007\/s11605-011-1680-x","article-title":"Focal nodular hyperplasia\u2014a review of myths and truths","volume":"15","author":"Nahm","year":"2011","journal-title":"J Gastrointest Surg"},{"key":"2023062616284859100_ref4","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1067\/mob.2002.120277","article-title":"Oral contraceptives and the risk of focal nodular hyperplasia of the liver: a case-control study","volume":"186","author":"Scalori","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"2023062616284859100_ref5","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/hpb.12387","article-title":"Oestrogen hormone receptors in focal nodular hyperplasia","volume":"17","author":"Chandrasegaram","year":"2015","journal-title":"HPB"},{"key":"2023062616284859100_ref6","doi-asserted-by":"crossref","first-page":"333","DOI":"10.5604\/16652681.1235475","article-title":"What is changing in indications and treatment of focal nodular hyperplasia of the liver. Is there any place for surgery?","volume":"16","author":"Perrakis","year":"2017","journal-title":"Ann Hepatol"},{"key":"2023062616284859100_ref7","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.jhep.2016.04.001","article-title":"EASL clinical practice guidelines on the management of benign liver tumours","volume":"65","author":"European Association for the Study of the Liver","year":"2016","journal-title":"J Hepatol"},{"volume-title":"Focal Nodular Hyperplasia","year":"2022","author":"Hamad","key":"2023062616284859100_ref8"},{"key":"2023062616284859100_ref9","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/S0140-6736(05)79318-1","article-title":"Pregnancy in women with observed focal nodular hyperplasia of the liver","volume":"351","author":"Weimann","year":"1998","journal-title":"Lancet"},{"key":"2023062616284859100_ref10","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.amjsurg.2003.11.016","article-title":"A review of liver masses in pregnancy and a proposed algorithm for their diagnosis and management","volume":"187","author":"Cobey","year":"2004","journal-title":"Am J Surg"},{"key":"2023062616284859100_ref11","doi-asserted-by":"crossref","first-page":"e00531","DOI":"10.14309\/crj.0000000000000531","article-title":"Estrogen-driven growth of focal nodular hyperplasia: truth or myth?","volume":"8","author":"Ashhab","year":"2021","journal-title":"ACG Case Rep J"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2023\/6\/omad054\/50705260\/omad054.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2023\/6\/omad054\/50705260\/omad054.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T17:32:43Z","timestamp":1687800763000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omad054\/7207663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omad054","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2023,6]]},"published":{"date-parts":[[2023,6,1]]},"article-number":"omad054"}}