{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:24:38Z","timestamp":1787793878742,"version":"build-2784847793"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T00:00:00Z","timestamp":1703116800000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Eosinophilic fasciitis (EF) is a rare inflammatory disease affecting various connective tissues. It is characterized by induration of the skin as well as scleroderma-like manifestations that are progressive and bilaterally symmetrical. Additionally, the joints and muscles are commonly involved, and rarely, there can be involvement of internal organs. The diagnosis of EF is based on clinical, laboratory, radiological, and a full-thickness skin biopsy involving the fascia. The biopsy is often diagnostic and shows eosinophilic inflammation. Systemic corticosteroids specifically prednisone and prednisolone remain the preferred treatment of choice and may be combined with immunosuppressive therapy in a subset of patients. We herein report a patient complaining of chronic nonspecific symptoms that were diagnosed with EF. The patient was treated with steroids with marked improvement of his overall condition.<\/jats:p>","DOI":"10.1093\/omcr\/omad131","type":"journal-article","created":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T22:42:52Z","timestamp":1703198572000},"source":"Crossref","is-referenced-by-count":2,"title":["Eosinophilic Fasciitis Presenting as Chronic Nonspecific Symptoms in a Young Adult"],"prefix":"10.1093","volume":"2023","author":[{"given":"Mansour","family":"Khaleel","sequence":"first","affiliation":[{"name":"Makassed Hospital Department of Internal Medicine, , Jerusalem, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9772-2365","authenticated-orcid":false,"given":"Mohammed","family":"Ayyad","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Al Quds University , Abu Dis, State of Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3358-5493","authenticated-orcid":false,"given":"Nabil C N","family":"Khalil","sequence":"additional","affiliation":[{"name":"Makassed Hospital Department of Internal Medicine, , Jerusalem, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Tarayrah","sequence":"additional","affiliation":[{"name":"Makassed Hospital Department of Internal Medicine, , Jerusalem, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muath","family":"Tumezeh","sequence":"additional","affiliation":[{"name":"Makassed Hospital Department of Internal Medicine, , Jerusalem, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9656-2961","authenticated-orcid":false,"given":"Sami","family":"Bannoura","sequence":"additional","affiliation":[{"name":"Makassed Hospital Department of Pathology, , Jerusalem, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,12,19]]},"reference":[{"key":"2023122122381082900_ref1","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.berh.2012.08.001","article-title":"Eosinophilic fasciitis (Shulman disease)","volume":"26","author":"Lebeaux","year":"2012","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"2023122122381082900_ref2","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.autrev.2014.01.019","article-title":"Diagnosis and classification of eosinophilic fasciitis","volume":"13","author":"Pinal-Fernandez","year":"2014","journal-title":"Autoimmun Rev"},{"key":"2023122122381082900_ref3","first-page":"63","article-title":"Eosinophilic fasciitis: a case report","volume":"25","author":"Londo\u00f1o Correa","year":"2018","journal-title":"Rev Colomb Reumatol Engl 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