{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:12:02Z","timestamp":1788541922193,"version":"build-2803163510"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T00:00:00Z","timestamp":1708041600000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Mucocutaneous leishmaniasis (MCL) is a leishmania infection; that usually affects the oral and nasal mucosa. The coexistence of leishmania and malignancy is rarely reported and mainly in immunocompromised patients. We report a case of an overlapping between leishmania and squamous cell carcinoma (SCC) in a 60-year-old immunocompetent Syrian female. The patient presented with a one-year crusty nodule on the lower lip. Since she lives in an endemic region, leishmaniasis was suggested, and confirmed with a Giemsa-stained smear. After 20\u00a0days of meglumine antimoniate treatment, the patient revealed no signs of recovery, thus, the treatment was prolonged with the addition of sodium stibogluconate injections. Later, she presented with increased symptoms. A biopsy was performed due to SCC suspicion, and it was verified. The patient underwent complete surgical removal of the lesion. After a one-year follow-up, no recurrence was observed. We illustrated the importance of considering SCC in cases of refractory leishmaniasis.<\/jats:p>","DOI":"10.1093\/omcr\/omad153","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T08:42:50Z","timestamp":1708159370000},"source":"Crossref","is-referenced-by-count":3,"title":["Overlapping between squamous cell carcinoma and mucocutaneous leishmaniasis in a diabetic patient"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3299-1780","authenticated-orcid":false,"given":"Hala","family":"Khaddam","sequence":"first","affiliation":[{"name":"Tartous University Faculty of Medicine, , Tartous, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9995-3204","authenticated-orcid":false,"given":"Kheder","family":"Kheder","sequence":"additional","affiliation":[{"name":"Al Basel Hospital Department of Ophthalmology, , Tartous, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4464-5877","authenticated-orcid":false,"given":"Rami","family":"Sabouni","sequence":"additional","affiliation":[{"name":"Damascus University Faculty of Medicine, , Damascus, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9483-509X","authenticated-orcid":false,"given":"Younes","family":"Al Mahmoud","sequence":"additional","affiliation":[{"name":"Tishreen University Hospital Neurology Department, , Latakia, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1284-7151","authenticated-orcid":false,"given":"Rasha","family":"Nabhan","sequence":"additional","affiliation":[{"name":"Duraykish National Hospital Department of Dermatology, , Tartous, Syria"},{"name":"Damascus University Board Certification in Skin Diseases, , Damascus, Syria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,2,16]]},"reference":[{"key":"2024021708422210500_ref1","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0140-6736(18)31204-2","article-title":"Leishmaniasis","volume":"392","author":"Burza","year":"2018","journal-title":"Lancet"},{"key":"2024021708422210500_ref2","doi-asserted-by":"crossref","first-page":"e70","DOI":"10.1111\/odi.12268","article-title":"Mucosal leishmaniasis with primary oral involvement: a case series and a review of the literature","volume":"21","author":"Mignogna","year":"2015","journal-title":"Oral Dis"},{"key":"2024021708422210500_ref3","doi-asserted-by":"crossref","DOI":"10.1186\/s12879-016-2178-7","article-title":"Lip leishmaniasis: a case series with molecular identification and literature review","volume":"17","author":"Mohammadpour","year":"2017","journal-title":"BMC Infect Dis"},{"key":"2024021708422210500_ref4","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1111\/tid.12380","article-title":"Mucosal leishmaniasis mimicking squamous cell carcinoma in a liver transplant recipient","volume":"17","author":"Ramos","year":"2015","journal-title":"Transpl Infect Dis"},{"key":"2024021708422210500_ref5","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1600-0560.2011.01844.x","article-title":"Cutaneous leishmaniasis mimicking inflammatory and neoplastic processes: a clinical, histopathological and molecular study of 57 cases","volume":"39","author":"Saab","year":"2012","journal-title":"J Cutan Pathol"},{"key":"2024021708422210500_ref6","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1177\/0956462420970842","article-title":"Squamous cell carcinoma superimposed on mucosal leishmaniasis in an HIV-positive patient","volume":"32","author":"Altobrando","year":"2021","journal-title":"Int J STD AIDS"},{"key":"2024021708422210500_ref7","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.trstmh.2007.08.003","article-title":"Aspects of the association between leishmaniasis and malignant disorders","volume":"101","author":"Kopterides","year":"2007","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"2024021708422210500_ref8","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.4269\/ajtmh.18-0243","article-title":"Case report: squamous cell carcinoma referred for Mohs surgery found to be cutaneous leishmaniasis","volume":"99","author":"Prieto","year":"2018","journal-title":"Am J Trop Med Hyg"},{"key":"2024021708422210500_ref9","doi-asserted-by":"crossref","DOI":"10.1097\/DAD.0b013e31820977d1","article-title":"Cutaneous leishmaniasis with pseudoepitheliomatous hyperplasia simulating squamous cell carcinoma","author":"Quintella","year":"2011"},{"key":"2024021708422210500_ref10","doi-asserted-by":"crossref","first-page":"110","DOI":"10.12688\/wellcomeopenres.15367.1","article-title":"Is there an association between cutaneous leishmaniasis and skin cancer? A systematic review [version 1; peer review: 2 approved]","volume":"4","author":"Carrillo-Larco","year":"2019","journal-title":"Wellcome Open Res"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2024\/2\/omad153\/56689545\/omad153.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2024\/2\/omad153\/56689545\/omad153.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T08:42:58Z","timestamp":1708159378000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omad153\/7609200"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,1]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omad153","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,2]]},"published":{"date-parts":[[2024,2,1]]},"article-number":"omad153"}}