{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:28:31Z","timestamp":1789756111198,"version":"4.0.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T00:00:00Z","timestamp":1708041600000},"content-version":"vor","delay-in-days":15,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most difficult-to-alleviate side effects of chemotherapy, impacting the patient\u2019s daily activities and quality of life and frequently necessitating the discontinuation or dose reduction of anticancer drugs. An effective treatment for CIPN is yet to be established. Herein, we report the case of a patient who developed CIPN after receiving paclitaxel as postoperative chemotherapy for breast cancer. The patient experienced difficulties in performing daily activities owing to pain in her fingers and toes despite attempts to treat these symptoms with medications. Stellate and lumbar sympathetic ganglion blocks improved CIPN-induced symptoms of numbness and pain in the extremities. Thereafter, lumbar sympathetic ganglion block was performed once every 6\u00a0months, markedly improving the patient\u2019s quality of life. Accordingly, sympathetic nerve block can facilitate pain control in patients with CIPN refractory to pharmacotherapy.<\/jats:p>","DOI":"10.1093\/omcr\/omae006","type":"journal-article","created":{"date-parts":[[2024,2,17]],"date-time":"2024-02-17T08:44:05Z","timestamp":1708159445000},"source":"Crossref","is-referenced-by-count":5,"title":["Effective sympathetic nerve block for chemotherapy-induced peripheral neuropathy: a case report"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9782-6870","authenticated-orcid":false,"given":"Aya","family":"Kuroyanagi","sequence":"first","affiliation":[{"name":"Saitama Cooperative Hospital Department of Anesthesiology, , Kawaguchi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiaki","family":"Inano","sequence":"additional","affiliation":[{"name":"Tokyo Metropolitan Police Hospital Department of Anesthesiology, , Nakano, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Adachi","sequence":"additional","affiliation":[{"name":"Saitama Cooperative Hospital Department of Anesthesiology, , Kawaguchi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goro","family":"Kaneko","sequence":"additional","affiliation":[{"name":"Saitama Cooperative Hospital Department of Anesthesiology, , Kawaguchi, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Toyokawa","sequence":"additional","affiliation":[{"name":"Tokyo Women\u2019s Medical University Department of Anesthesiology, , Shinjuku, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,2,16]]},"reference":[{"key":"2024021708434863900_ref1","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1001\/jama.2013.2813","article-title":"Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial","volume":"309","author":"Lavoie Smith","year":"2013","journal-title":"JAMA"},{"key":"2024021708434863900_ref2","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1200\/JCO.2013.54.0914","article-title":"Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline","volume":"32","author":"Hershman","year":"2014","journal-title":"J Clin Oncol"},{"key":"2024021708434863900_ref3","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.2147\/JPR.S134775","article-title":"Ganglion blocks as a treatment of pain: current perspectives","volume":"10","author":"Gunduz","year":"2017","journal-title":"J Pain Res"},{"key":"2024021708434863900_ref4","first-page":"285328","article-title":"Sympathetic blocks provided sustained pain relief in a patient with refractory painful diabetic neuropathy","volume":"2012","author":"Cheng","year":"2012","journal-title":"Case Rep Anesthesiol"},{"key":"2024021708434863900_ref5","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.626687","article-title":"Neuroinflammatory process involved in different preclinical models of chemotherapy-induced peripheral neuropathy","volume":"11","author":"Fumagalli","year":"2021","journal-title":"Front Immunol"},{"key":"2024021708434863900_ref6","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1007\/s00520-021-06042-x","article-title":"Chemotherapy-induced peripheral neuropathy (CIPN): current therapies and topical treatment option with high-concentration capsaicin","volume":"29","author":"Maih\u00f6fner","year":"2021","journal-title":"Support Care Cancer"},{"key":"2024021708434863900_ref7","doi-asserted-by":"crossref","first-page":"419","DOI":"10.3322\/caac.21204","article-title":"Chemotherapy-induced peripheral neurotoxicity: a critical analysis","volume":"63","author":"Park","year":"2013","journal-title":"CA Cancer J Clin"},{"key":"2024021708434863900_ref8","doi-asserted-by":"crossref","first-page":"174","DOI":"10.3389\/fnmol.2017.00174","article-title":"Pathophysiology of chemotherapy-induced peripheral neuropathy","volume":"10","author":"Starobova","year":"2017","journal-title":"Front Mol Neurosci"},{"key":"2024021708434863900_ref9","doi-asserted-by":"crossref","first-page":"216","DOI":"10.24015\/JAPM.2015.0029","article-title":"Progress in sympathetically mediated pathological pain","volume":"2","author":"Chen","year":"2015","journal-title":"J Anesth Perioper Med"},{"key":"2024021708434863900_ref10","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1177\/0363546505274957","article-title":"Chronic exercise-induced leg pain in an athlete successfully treated with sympathetic block","volume":"33","author":"Gebauer","year":"2005","journal-title":"Am J Sports Med"}],"container-title":["Oxford Medical Case 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