{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:04:41Z","timestamp":1753877081508,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Hashimoto\u2019s thyroiditis is an autoimmune thyroid disease characterized by lymphocytic infiltration and thyroid-specific autoantibodies. Hashimoto\u2019s encephalopathy, a rare entity associated with these antibodies, presents as a relapsing encephalopathy with neuropsychiatric manifestations and seizures. A 15-year-old girl, initially healthy, experienced a tonic-clonic seizure. Despite unremarkable initial assessments, she returned with generalized convulsive status epilepticus. Hashimoto\u2019s thyroiditis was suggested by elevated thyroid-stimulating hormone levels, low thyroxine levels, and high anti-thyroid antibodies, and was confirmed by ultrasound. Steroids were not used initially due to seizure cessation with anesthesia. Post-treatment with levothyroxine and antiepileptics, she was seizure-free at follow-up and eventually maintained solely on levothyroxine. Hashimoto\u2019s encephalopathy, characterized by diverse symptoms, often necessitates corticosteroids, immunoglobulins, and plasmapheresis, as traditional anti-seizure medications fail. Further research into its etiology and pathophysiology is essential. Consider Hashimoto\u2019s encephalopathy in unexplained seizures, especially with ineffective standard treatments. Pediatric diagnostic criteria need to be revisited.<\/jats:p>","DOI":"10.1093\/omcr\/omae031","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T15:23:15Z","timestamp":1714144995000},"source":"Crossref","is-referenced-by-count":0,"title":["Refractory status epilepticus in a pediatric patient: Exploring the association with thyroid dysfunction"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4489-6166","authenticated-orcid":false,"given":"Alaa","family":"Hmeedan","sequence":"first","affiliation":[{"name":"An-Najah National University Internal Medicine Department, , Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3065-5396","authenticated-orcid":false,"given":"Hadi Adnan","family":"Rabee","sequence":"additional","affiliation":[{"name":"Al-Watani Hospital Internal Medicine Specialist, , Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8617-237X","authenticated-orcid":false,"given":"Mahmoud","family":"Doudein","sequence":"additional","affiliation":[{"name":"Specialized Arab Hospital Internal Medicine Department, , Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8300-0262","authenticated-orcid":false,"given":"Abdalhakim R M","family":"Shubietah","sequence":"additional","affiliation":[{"name":"Jaffa Specialized Surgical Hospital Medical Surgical Department, , Ramallah, Palestine"},{"name":"An-Najah National University Faculty of Medicine and Health Sciences, , Nablus, Palestine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,4,25]]},"reference":[{"key":"2024050511210948100_ref1","first-page":"16222","article-title":"Hashimoto thyroiditis: an evidence-based guide to etiology, diagnosis and 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