{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T08:28:58Z","timestamp":1765268938824,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T00:00:00Z","timestamp":1716336000000},"content-version":"vor","delay-in-days":21,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We report the case of a 5-year-old boy diagnosed with congenital adrenal hyperplasia due to 11-hydroxylase deficiency, revealed by disorders of sex development (DSD) and acute pulmonary edema due to severe hypertension. We considered the diagnosis based on biological and radiological examinations. The sociocultural background and the delayed diagnosis had a significant impact on the therapeutic decisions. All babies should be screened for 11 beta-hydroxylase deficiency, there should be specialized and interdisciplinary medical centers, and early detection is essential to avoiding serious complications of this disease.<\/jats:p>","DOI":"10.1093\/omcr\/omae042","type":"journal-article","created":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T16:36:47Z","timestamp":1716395807000},"source":"Crossref","is-referenced-by-count":1,"title":["A rare case of steroid 11 beta-hydroxylase deficiency in a child revealed by acute pulmonary edema"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0419-7691","authenticated-orcid":false,"given":"Zohair","family":"El Haddar","sequence":"first","affiliation":[{"name":"Mohammed VI University Hospital Department of Pediatrics, , Oujda, Morocco"},{"name":"Mohammed Ist University Faculty of Medicine and Pharmacy, , Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aziza","family":"El ouali","sequence":"additional","affiliation":[{"name":"Mohammed VI University Hospital Department of Pediatrics, , Oujda, Morocco"},{"name":"Mohammed Ist University Faculty of Medicine and Pharmacy, , Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayad","family":"Ghanam","sequence":"additional","affiliation":[{"name":"Mohammed VI University Hospital Department of Pediatrics, , Oujda, Morocco"},{"name":"Mohammed Ist University Faculty of Medicine and Pharmacy, , Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noufissa","family":"Benajiba","sequence":"additional","affiliation":[{"name":"Mohammed VI University Hospital Department of Pediatrics, , Oujda, Morocco"},{"name":"Mohammed Ist University Faculty of Medicine and Pharmacy, , Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Rkain","sequence":"additional","affiliation":[{"name":"Mohammed VI University Hospital Department of Pediatrics, , Oujda, Morocco"},{"name":"Mohammed Ist University Faculty of Medicine and Pharmacy, , Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdeladim","family":"Babakhouya","sequence":"additional","affiliation":[{"name":"Mohammed VI University Hospital Department of Pediatrics, , Oujda, Morocco"},{"name":"Mohammed Ist University Faculty of Medicine and Pharmacy, , Oujda, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,20]]},"reference":[{"key":"2024052214565959200_ref1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s12020-016-1189-x","article-title":"Clinical perspectives in congenital adrenal hyperplasia due to 11\u03b2-hydroxylase deficiency","volume":"55","author":"Bulsari","year":"2017","journal-title":"Endocrine"},{"key":"2024052214565959200_ref2","doi-asserted-by":"crossref","first-page":"E1933","DOI":"10.1073\/pnas.1621082114","article-title":"Clinical, genetic, and structural basis of congenital adrenal hyperplasia due to 11\u03b2-hydroxylase deficiency","volume":"114","author":"Khattab","year":"2017","journal-title":"Proc Natl Acad Sci USA"},{"key":"2024052214565959200_ref3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.beem.2015.04.010","article-title":"Inherited forms of mineralocorticoid hypertension","volume":"29","author":"Zennaro","year":"2015","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"2024052214565959200_ref4","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000442975","article-title":"Global disorders of sex development update since 2006: perceptions, approach and care","volume":"85","author":"Lee","year":"2016","journal-title":"Horm Res 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deficiency","volume":"96","author":"Sun","year":"2022","journal-title":"Clin Endocrinol"},{"key":"2024052214565959200_ref8","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/imj.12074","article-title":"Ambiguous genitalia and hypertension in a patient with congenital adrenal hyperplasia","volume":"43","author":"Valsalan","year":"2013","journal-title":"Intern Med J"},{"key":"2024052214565959200_ref9","doi-asserted-by":"crossref","first-page":"e3714","DOI":"10.1210\/clinem\/dgab225","article-title":"Clinical and hormonal profiles correlate with molecular characteristics in patients with 11\u03b2-hydroxylase deficiency","volume":"106","author":"Yildiz","year":"2021","journal-title":"J Clin Endocrinol Metab"},{"key":"2024052214565959200_ref10","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s00431-017-2864-5","article-title":"Hypospadias, all there is to know","volume":"176","author":"Horst","year":"2017","journal-title":"Eur J Pediatr"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2024\/5\/omae042\/57760474\/omae042.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2024\/5\/omae042\/57760474\/omae042.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T16:36:54Z","timestamp":1716395814000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omae042\/7676494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,1]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omae042","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2024,5]]},"published":{"date-parts":[[2024,5,1]]},"article-number":"omae042"}}