{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T18:33:06Z","timestamp":1787682786229,"version":"build-2784847793"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Takayasu\u2019s arteritis (TA), also known as pulseless disease and young female arteritis, is a chronic inflammatory large-vessel vasculitis (LVV). TA is pathologically characterized by arterial wall thickening, stenotic\/occlusive lesions, aneurysm formation, and dissection. TA usually develops between 20 and 30\u00a0years of age. However, pregnancy and puerperium can affect the immune system, and several cases of postpartum onset or flare-up of TA have been reported. Herein, we report an extremely rare case of postpartum-onset TA complicated by aortic dissection. This is a case of Postpartum onset Takayasu\u2019s arteritis presenting with aortic dissection. A 34-year-old healthy woman was performed cesarean section. After 2\u00a0weeks, she presented with chest pain and fever, followed by mild dysphagia and hoarseness. Laboratory findings showed C-reactive protein (CRP) 21.61\u00a0mg\/dl and computed tomography (CT) demonstrated thickening of the vessel wall of mainly ascending aorta. 18F-fluorodeoxyglucose (FDG)-position emission tomography (PET)\/CT revealed high FDG uptake in the same areas. We diagnosed with TA and steroid pulse therapy was started. However, five days after treatment, the patient developed worsening symptoms of hoarseness. A contrast-enhanced CT showed Stanford A type dissection, and emergency artificial vessel replacement was performed. The specimen from surgical resection of the ascending aorta suggested active TA associated with dissection. The prednisolone dosage was gradually tapered with tocilizumab. Then, her symptoms and laboratory findings improved. It is important to recall the onset of TA and\/or arterial dissection, when patients develop chest pain and hoarseness in the postpartum period.<\/jats:p>","DOI":"10.1093\/omcr\/omae078","type":"journal-article","created":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T02:07:32Z","timestamp":1722478052000},"source":"Crossref","is-referenced-by-count":3,"title":["Postpartum onset Takayasu\u2019s arteritis presenting with aortic dissection"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0402-2838","authenticated-orcid":false,"given":"Hirotaka","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Kochi University Department of Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi Medical School Hospital, , 185-1 Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Taniguchi","sequence":"additional","affiliation":[{"name":"Kochi University Department of Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi Medical School Hospital, , 185-1 Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujiro","family":"Miura","sequence":"additional","affiliation":[{"name":"Kochi University Department of Cardiovascular Surgery, Kochi Medical School Hospital, , 185-1 Kohasu, Oko-cho, Nankoku, Kochi 783-8505, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1939-3380","authenticated-orcid":false,"given":"Shigeto","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Juntendo Koshigaya Hospital Department of Internal Medicine (Rheumatology), , 560 Fukuroyama, Koshigaya, Saitama 343-0032, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,7,30]]},"reference":[{"key":"2024073112354820000_ref1","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.jacc.2022.09.051","article-title":"Takayasu arteritis: JACC focus seminar 3\/4","volume":"81","author":"Joseph","year":"2022","journal-title":"J Am Coll Cardiol"},{"key":"2024073112354820000_ref2","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/s40748-023-00147-3","article-title":"Systemic vasculitis diagnosed during the post-partum period: case report and review of the literature","volume":"9","author":"Demotier","year":"2023","journal-title":"Matern Health Neonatol Perinatol"},{"key":"2024073112354820000_ref3","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1002\/art.39335","article-title":"Takayasu arteritis and pregnancy","volume":"67","author":"Comarmond","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"2024073112354820000_ref4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12948-016-0048-x","article-title":"How pregnancy can affect autoimmune diseases progression?","volume":"14","author":"Piccinni","year":"2016","journal-title":"Clin Mol Allergy"},{"key":"2024073112354820000_ref5","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.4049\/jimmunol.180.4.2029","article-title":"Cutting edge: progesterone regulates IFN-alpha production by plasmacytoid dendritic cells","volume":"180","author":"Hughes","year":"2008","journal-title":"J Immunol"},{"key":"2024073112354820000_ref6","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.1093\/eurheartj\/ehaa497","article-title":"Pregnancy-associated arterial dissections: a nationwide cohort study","volume":"41","author":"Beyer","year":"2020","journal-title":"Eur Heart J"},{"key":"2024073112354820000_ref7","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1056\/NEJM199906103402306","article-title":"The protective effects of estrogen on the cardiovascular system","volume":"340","author":"Mendelsohn","year":"1999","journal-title":"N Engl J Med"},{"key":"2024073112354820000_ref8","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1111\/jog.14657","article-title":"Aortic dissection during pregnancy and puerperium: a Japanese nationwide survey","volume":"47","author":"Tanaka","year":"2021","journal-title":"J Obstet Gynaecol Res"},{"key":"2024073112354820000_ref9","first-page":"485","article-title":"Clinical features of aortic dissection associated with Takayasu's arteritis","volume":"14","author":"Wu","year":"2017","journal-title":"J Geriatr Cardiol"},{"key":"2024073112354820000_ref10","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12969-016-0115-3","article-title":"Arterial dissection in childhood Takayasu arteritis: not as rare as thought","volume":"14","author":"Aeschlimann","year":"2016","journal-title":"Pediatr Rheumatol Online J"},{"key":"2024073112354820000_ref11","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s13075-020-02396-5","article-title":"French study Group for Large Vessel Vasculitis (GEFA). Symptomatic aortitis at giant cell arteritis diagnosis: a prognostic factor of aortic event","volume":"23","author":"Espitia","year":"2021","journal-title":"Arthritis Res Ther"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2024\/7\/omae078\/58689634\/omae078.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2024\/7\/omae078\/58689634\/omae078.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T02:07:39Z","timestamp":1722478059000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omae078\/7724003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omae078","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,7]]},"published":{"date-parts":[[2024,7,1]]},"article-number":"omae078"}}