{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:12:03Z","timestamp":1753877523197,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T00:00:00Z","timestamp":1725667200000},"content-version":"vor","delay-in-days":6,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>We conducted clinical and histological evaluations on two male patients who presented with corneal keloid. One patient had a history of corneal trauma due to contact with boiling sunflower oil, while the other had undergone pterygium removal. Upon slit lamp examination, the corneal lesions were identified as single, well-circumscribed, pearly white nodules with a smooth surface. We successfully removed these nodules using a combination of superficial keratectomy and the application of mitomycin C. Light microscopy analysis of the excised nodules revealed hyperplastic epithelium, disrupted Bowman\u2019s layer, and irregularly arranged abundant collagen fibers within the stroma. Notably, there was no recurrence of the lesions in either case within six months following the surgical excision. Secondary corneal keloids should be considered as a potential diagnosis in patients with elevated corneal nodules, especially when there is a history of ocular surface trauma or surgery.<\/jats:p>","DOI":"10.1093\/omcr\/omae105","type":"journal-article","created":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T12:23:39Z","timestamp":1725711819000},"source":"Crossref","is-referenced-by-count":0,"title":["Secondary corneal keloid: a report of two cases"],"prefix":"10.1093","volume":"2024","author":[{"given":"Ali","family":"Sharifi","sequence":"first","affiliation":[{"name":"Clinical Research Development Unit, Shafa Hospital , Shafa St. 7616913555, Kerman, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Touraj-Reza","family":"Mirshekari","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit, Shafa Hospital , Shafa St. 7616913555, Kerman, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milad","family":"Azh","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit, Shafa Hospital , Shafa St. 7616913555, Kerman, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit, Shafa Hospital , Shafa St. 7616913555, Kerman, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Akbari","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Kerman University of Medical Sciences , Haft-bagh Highway 7616913555, Kerman, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4423-4979","authenticated-orcid":false,"given":"Amin","family":"Zand","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit, Shafa Hospital , Shafa St. 7616913555, Kerman, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,9,7]]},"reference":[{"key":"2024090709150737800_ref1","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/S1542-0124(12)70179-9","article-title":"Corneal keloid","volume":"6","author":"Vanathi","year":"2008","journal-title":"Ocul Surf"},{"key":"2024090709150737800_ref2","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1097\/ICO.0b013e3182a73a10","article-title":"Corneal keloid","volume":"32","author":"Bakhtiari","year":"2013","journal-title":"Cornea"},{"key":"2024090709150737800_ref3","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/00003226-200105000-00017","article-title":"Clinical, surgical, and histopathologic characteristics of corneal keloid","volume":"20","author":"Mej\u00eda","year":"2001","journal-title":"Cornea"},{"key":"2024090709150737800_ref4","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1001\/archopht.1982.01030040775013","article-title":"Corneal keloid in Lowe\u2019s syndrome","volume":"100","author":"Cibis","year":"1982","journal-title":"Arch Ophthalmol"},{"key":"2024090709150737800_ref5","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1186\/s12886-016-0372-4","article-title":"Corneal keloid: four case reports of clinicopathological features and surgical outcome","volume":"16","author":"Lee","year":"2016","journal-title":"BMC Ophthalmol"},{"key":"2024090709150737800_ref6","doi-asserted-by":"crossref","first-page":"e252776","DOI":"10.1136\/bcr-2022-252776","article-title":"Rare case of corneal keloid following radial keratotomy for myopia","volume":"16","author":"Gupta","year":"2023","journal-title":"BMJ Case Rep"},{"key":"2024090709150737800_ref7","doi-asserted-by":"crossref","first-page":"101819","DOI":"10.1016\/j.ajoc.2023.101819","article-title":"Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure","volume":"30","author":"Minamidate","year":"2023","journal-title":"Am J Ophthalmol Case Rep"},{"key":"2024090709150737800_ref8","doi-asserted-by":"crossref","first-page":"e93","DOI":"10.1016\/j.jcjo.2016.11.013","article-title":"Corneal keloid with cystoid cicatrix:post\u2013small-incision cataract surgery","volume":"52","author":"Singh","year":"2017","journal-title":"Can J Ophthalmol"},{"key":"2024090709150737800_ref9","doi-asserted-by":"crossref","first-page":"100901","DOI":"10.1016\/j.ajoc.2020.100901","article-title":"A rare case of corneal keloid occurred 30 years after pterygium surgery and 3 years after cataract surgery","volume":"20","author":"Miyamoto","year":"2020","journal-title":"Am J Ophthalmol Case 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