{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:14:55Z","timestamp":1790900095069,"version":"4.1.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Aim: To report a patient with choroidal bulging, sub-retinal fluid, and optic nerve head (ONH) swelling who was finally diagnosed with focal nodular posterior scleritis. Case report: A 51-year-old male patient presented to us with acute painful visual loss of his left eye (LE) from 3\u00a0days ago. The best-corrected distance visual acuity (BCDVA) was 20\/20 and hand motion (HM) for the right eye (RE) and LE, respectively. Fundus examination of the LE showed ONH swelling, choroidal bulging, multiple patches of subretinal fluid accumulation, and retinal pigment epithelial (RPE) corrugations. Orbital and brain MRI showed a retrobulbar nodular mass with gadolinium enhancement at the optic nerve and sclera junction. Oncology and rheumatology work-ups were unremarkable. With the clinical diagnosis of nodular posterior scleritis oral prednisolone 50\u00a0mg\/Kg was started. Conclusion: Posterior scleritis is an uncommon inflammatory condition that could be misdiagnosed with choroidal tumors, posterior uveitis, and orbital inflammation.<\/jats:p>","DOI":"10.1093\/omcr\/omae146","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T11:18:59Z","timestamp":1732533539000},"source":"Crossref","is-referenced-by-count":2,"title":["Posterior localized nodular scleritis mimicking malignancy, a case report and clinical approach"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8680-5560","authenticated-orcid":false,"given":"Mehrdad","family":"Motamed Shariati","sequence":"first","affiliation":[{"name":"Mashhad University of Medical Sciences Eye Research Center, , Khatam Al-Anbia Eye Hospital, Gharani Boulevard, Mashhad,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farid","family":"Shekarchian","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences Eye Research Center, , Khatam Al-Anbia Eye Hospital, Gharani Boulevard, Mashhad,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliakbar","family":"Sabermoghaddam","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences Eye Research Center, , Khatam Al-Anbia Eye Hospital, Gharani Boulevard, Mashhad,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra Karimi Amir","family":"Abadi","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences Eye Research Center, , Khatam Al-Anbia Eye Hospital, Gharani Boulevard, Mashhad,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasser","family":"Shoeibi","sequence":"additional","affiliation":[{"name":"Mashhad University of Medical Sciences Eye Research Center, , Khatam Al-Anbia Eye Hospital, Gharani Boulevard, Mashhad,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"key":"2024112511184682800_ref1","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.18240\/ijo.2019.07.16","article-title":"The clinical features of posterior scleritis with serous retinal detachment: a retrospective clinical analysis","volume":"12","author":"Dong","year":"2019","journal-title":"Int J Ophthalmol"},{"key":"2024112511184682800_ref2","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4103\/meajo.MEAJO_115_20","article-title":"Multimodal imaging of nodular posterior Scleritis: case report and review of the literature","volume":"27","author":"Alsarhani","year":"2020","journal-title":"Middle East Afr J Ophthalmol"},{"key":"2024112511184682800_ref3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1080\/09273948.2019.1574838","article-title":"Clinical features, treatment, and visual outcomes of Japanese patients with posterior scleritis","volume":"28","author":"Ando","year":"2020","journal-title":"Ocul Immunol Inflamm"},{"key":"2024112511184682800_ref4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12348-021-00269-9","article-title":"Choroidal involvement in non-infectious posterior scleritis","volume":"11","author":"Vermeirsch","year":"2021","journal-title":"J Ophthalmic Inflamm Infect"},{"key":"2024112511184682800_ref5","doi-asserted-by":"crossref","first-page":"100583","DOI":"10.1016\/j.ajoc.2019.100583","article-title":"A case of giant cell arteritis presenting with nodular posterior scleritis mimicking a choroidal mass","volume":"17","author":"Awh","year":"2020","journal-title":"Am J Ophthalmol Case Rep"},{"key":"2024112511184682800_ref6","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1007\/s00417-012-1972-1","article-title":"Enhanced depth imaging optical coherence tomography of the choroid in recurrent unilateral posterior scleritis","volume":"251","author":"Taki","year":"2013","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"2024112511184682800_ref7","doi-asserted-by":"crossref","first-page":"305","DOI":"10.5694\/j.1326-5377.2010.tb03915.x","article-title":"Posterior scleritis mimicking orbital cellulitis","volume":"193","author":"Rossiter-Thornton","year":"2010","journal-title":"Med J Aust"},{"key":"2024112511184682800_ref8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.5935\/0004-2749.20160032","article-title":"Isolated posterior scleritis associated with tuberculosis","volume":"79","author":"Miranda","year":"2016","journal-title":"Arq Bras Oftalmol"},{"key":"2024112511184682800_ref9","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s10792-013-9894-4","article-title":"Choroidal observations in posterior scleritis using high-penetration optical coherence tomography","volume":"34","author":"Uchihori","year":"2014","journal-title":"Int 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Inflamm"},{"key":"2024112511184682800_ref13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1038\/ncprheum0454","article-title":"Therapy insight: scleritis and its relationship to systemic autoimmune disease","volume":"3","author":"Smith","year":"2007","journal-title":"Nat Clin Pract Rheumatol"},{"key":"2024112511184682800_ref14","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ophtha.2003.06.006","article-title":"Evaluation of patients with scleritis for systemic disease","volume":"111","author":"Akpek","year":"2004","journal-title":"Ophthalmology"}],"container-title":["Oxford Medical Case 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