{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T21:11:32Z","timestamp":1766178692948,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"vor","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Strongyloides stercoralis is an intestinal nematode. It is widely distributed in the tropics and sub-tropics of the world. It can cause a wide array of illnesses ranging from asymptomatic autoinfection to a severe form of hyperinfection and disseminated strongyloidiasis. Here we report a case of a 73-year-old patient presenting with obstructive shock with bipedal edema without any evidence of adrenal insufficiency. An upper gastrointestinal endoscopy revealed Strongyloides larva in the lumen of duodenal crypts. Stool examination and broncho-alveolar lavage revealed the presence of S. stercoralis larva. Computed tomography of pulmonary angiography revealed pulmonary thromboembolism. A long segment thrombus was also noted in the right external iliac vein on color Doppler with negative screening for malignancy on computed tomography scan. This case suggests that pulmonary thromboembolism with anemia and hypoalbuminemia could be a rare presentation of a systemic illness like Strongyloides hyperinfection in an immunocompetent patient from the tropics.<\/jats:p>","DOI":"10.1093\/omcr\/omae152","type":"journal-article","created":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T02:12:23Z","timestamp":1733883143000},"source":"Crossref","is-referenced-by-count":1,"title":["Pulmonary thromboembolism\u2014a rare presentation for Strongyloides hyperinfection in an immunocompetent patient"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8988-5092","authenticated-orcid":false,"given":"Mir Wasim","family":"Ali","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, IPGMER & SSKM Hospital , 242 Harish Mukherjee Road, Kolkata 700020,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soumadip","family":"Rakshit","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, IPGMER & SSKM Hospital , 242 Harish Mukherjee Road, Kolkata 700020,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atreyee","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of Pathology, IPGMER & SSKM Hospital , 242 Harish Mukherjee Road, Kolkata 700020,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Karimulla","family":"Mondal","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, IPGMER & SSKM Hospital , 242 Harish Mukherjee Road, Kolkata 700020,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anup Kumar","family":"Datta","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, IPGMER & SSKM Hospital , 242 Harish Mukherjee Road, Kolkata 700020,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uttara","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Pathology, IPGMER & SSKM Hospital , 242 Harish Mukherjee Road, Kolkata 700020,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,12,10]]},"reference":[{"key":"2024121101373988900_ref1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.14745\/ccdr.v42i01a03","article-title":"CATMAT statement on disseminated strongyloidiasis: prevention, assessment and management guidelines","volume":"42","author":"Boggild","year":"2016","journal-title":"Can Commun Dis Rep"},{"key":"2024121101373988900_ref2","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1503\/cmaj.1031698","article-title":"Complicated and fatal Strongyloides infection in Canadians: risk factors, diagnosis and management","volume":"171","author":"Lim","year":"2004","journal-title":"CMAJ"},{"key":"2024121101373988900_ref3","doi-asserted-by":"publisher","first-page":"418","DOI":"10.4269\/ajtmh.19-0347","article-title":"Case report: two cases of Strongyloidiasis presenting with thrombotic events","volume":"101","author":"Waters","year":"2019","journal-title":"Am J Trop Med Hyg"},{"key":"2024121101373988900_ref4","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1345\/aph.1K302","article-title":"Manifestations, diagnosis, and treatment of Strongyloides stercoralis infection","volume":"41","author":"Segarra-Newnham","year":"2007","journal-title":"Ann Pharmacother"},{"key":"2024121101373988900_ref5","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1073\/pnas.0610193104","article-title":"Urocanic acid is a major chemoattractant for the skin-penetrating parasitic nematode Strongyloides stercoralis","volume":"104","author":"Safer","year":"2007","journal-title":"Proc Natl Acad Sci"},{"key":"2024121101373988900_ref6","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s11908-010-0150-z","article-title":"Update on Strongyloidiasis in the immunocompromised host","volume":"13","author":"Marcos","year":"2011","journal-title":"Curr Infect Dis Rep"},{"key":"2024121101373988900_ref7","doi-asserted-by":"crossref","first-page":"e18094","DOI":"10.1016\/j.heliyon.2023.e18094","article-title":"Gastroduodenal strongyloidiasis infection causing protein-losing enteropathy: a case report and review of the literature","volume":"9","author":"Wang","year":"2023","journal-title":"Heliyon"},{"key":"2024121101373988900_ref8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1128\/CVI.00278-06","article-title":"Evaluation of an indirect immunofluorescence assay for strongyloidiasis as a tool for diagnosis and follow-up","volume":"14","author":"Boscolo","year":"2007","journal-title":"Clin Vaccine 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