{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:40:14Z","timestamp":1759048814247,"version":"3.44.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T00:00:00Z","timestamp":1737158400000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Background: Saprochaete capitata may cause fatal infections in immunocompromised patients. This is the first case report of invasive Saprochaete capitate infection at an academic-tertiary care center in Palestine. Case presentation: We report a 36\u2014year\u2014old woman who presented with fever and severe neutropenia and was found to have AML\/Non M3. While receiving her initial chemotherapy treatment, she encountered a rare fungal infection (Saprochaete capitata) that spread throughout her lungs, stomach, spleen, liver, and kidneys, presenting difficulties in both diagnosing and treatment. In addition to being treated with both voriconazole and amphotericin B, the patient underwent surgery to remove the infection source, resulting in a cure. Conclusion: In immunocompromised patients, Saprochaete capitata infection is frequently overlooked. It is essential to give antifungal combinations and to control the source of infection to enhance the outcome for patients.<\/jats:p>","DOI":"10.1093\/omcr\/omae176","type":"journal-article","created":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T08:30:23Z","timestamp":1737189023000},"source":"Crossref","is-referenced-by-count":0,"title":["Disseminated fungal infection with <i>Saprochaete capitata<\/i> in acute myeloid leukemia patient: a case report from a developing country"],"prefix":"10.1093","volume":"2025","author":[{"given":"Mamoun W","family":"Swaileh","sequence":"first","affiliation":[{"name":"An-Najah National University Hospital Department of Internal Medicine, , Nablus 44839, West Bank,","place":["Palestine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman","family":"Dawoud","sequence":"additional","affiliation":[{"name":"An-Najah National University Hospital Department of Microbiology, , Nablus 44839, West Bank,","place":["Palestine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Razan","family":"Malhis","sequence":"additional","affiliation":[{"name":"An-Najah National University Hospital Hematology and Oncology Department, , Nablus 44839, West Bank,","place":["Palestine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1086-5565","authenticated-orcid":false,"given":"Banan M","family":"Aiesh","sequence":"additional","affiliation":[{"name":"An-Najah National University Hospital Infection Control Department, , Nablus 44839, West Bank,","place":["Palestine"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,1,18]]},"reference":[{"key":"2025092804214716000_ref1","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/j.riam.2013.02.004","article-title":"Invasive infections caused by Saprochaete capitata in patients with haematological malignancies: report of five cases and review of the antifungal therapy","volume":"30","author":"Garc\u00eda-Ruiz","year":"2013","journal-title":"Rev Iberoam Micol"},{"key":"2025092804214716000_ref2","doi-asserted-by":"publisher","first-page":"e0183421","DOI":"10.1128\/aac.01834-21","article-title":"Bloodstream infections caused by Magnusiomyces capitatus and Magnusiomyces clavatus: epidemiological, clinical, and microbiological features of two emerging yeast species","volume":"66","author":"Noster","year":"2022","journal-title":"Antimicrob Agents Chemother"},{"key":"2025092804214716000_ref3","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.mmcr.2019.07.009","article-title":"Magnusiomyces capitatus fungemia: the value of direct microscopy in early diagnosis","volume":"25","author":"Alobaid","year":"2019","journal-title":"Med Mycol Case Rep"},{"key":"2025092804214716000_ref4","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/j.diagmicrobio.2008.08.008","article-title":"Galactomannan detection in Geotrichum capitatum invasive infections: report of 2 new cases and review of diagnostic options","volume":"62","author":"Bonini","year":"2008","journal-title":"Diagn Microbiol Infect Dis"},{"key":"2025092804214716000_ref5","doi-asserted-by":"publisher","first-page":"3432","DOI":"10.1128\/JCM.00856-06","article-title":"Aspergillus galactomannan enzyme-linked immunosorbent assay cross-reactivity caused by invasive Geotrichum capitatum","volume":"44","author":"Giacchino","year":"2006","journal-title":"J Clin Microbiol"},{"key":"2025092804214716000_ref6","doi-asserted-by":"publisher","first-page":"e375","DOI":"10.1016\/S1473-3099(21)00203-6","article-title":"Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM","volume":"21","author":"Chen","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"2025092804214716000_ref7","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1590\/S1517-838246220120447","article-title":"Invasive infection due to Saprochaete capitata in a young patient with hematological malignancies. Braz","volume":"46","author":"Parahym","year":"2015","journal-title":"J Microbiol"},{"key":"2025092804214716000_ref8","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1080\/23744235.2016.1176246","article-title":"Molecular epidemiology and antifungal susceptibility of Saprochaete capitata (Blastoschizomyces capitatus) isolates causing nosocomial infection in Kayseri\/Turkey","volume":"48","author":"Ko\u00e7","year":"2016","journal-title":"Infect Dis (Lond)"},{"key":"2025092804214716000_ref9","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1097\/BS9.0000000000000022","article-title":"Surgical management of invasive fungal infections in adult leukemia patients: experience from a large tertiary center in Southeast-Asia","volume":"2","author":"Keng","year":"2020","journal-title":"Blood Sci"},{"key":"2025092804214716000_ref10","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.mmcr.2012.08.005","article-title":"Splenectomy as an effective debulking therapy for disseminated mould infection in acute myeloid leukaemia following adjuvant therapy with interferon gamma and liposomal amphotericin","volume":"1","author":"Latif","year":"2012","journal-title":"Med Mycol Case Rep"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/1\/omae176\/61490510\/omae176.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/1\/omae176\/61490510\/omae176.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:21:54Z","timestamp":1759047714000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omae176\/7959918"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,18]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omae176","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2025,1]]},"published":{"date-parts":[[2025,1]]},"article-number":"omae176"}}