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Degenerative changes are viewed as responses to injuries, whether mechanical or metabolic, rather than as distinct diseases. Degenerative disc disease is a frequent etiology of low back pain. Magnetic resonance imaging (MRI) commonly demonstrates disc desiccation, degeneration, herniation or protrusion, osteophyte formation, and facet joint arthropathy. In this case report we have specifically addressed a component of degenerative disc disease which is seen as an uncommon MRI finding of focal intradiscal fat. Although the direct impact of focal intradiscal fat on patient outcomes is not fully understood, it typically indicates advanced disc degeneration. Recognizing this finding can assist clinicians in diagnosing the extent of disc degeneration and developing appropriate treatment plans for patients with low back pain or related symptoms.<\/jats:p>","DOI":"10.1093\/omcr\/omaf027","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T14:09:30Z","timestamp":1748441370000},"source":"Crossref","is-referenced-by-count":1,"title":["Focal fatty infiltration of the lumbar intervertebral disc: a case report and literature review"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5051-2037","authenticated-orcid":false,"given":"Shritik","family":"Devkota","sequence":"first","affiliation":[{"name":"Department of Radiodiagnosis & Imaging, Postgraduate Institute of Medical Education and Research , Sector-12, Chandigarh , 160012,","place":["India"]},{"name":"Department of Radiodiagnosis & Imaging, Anil Baghi Hospital , Punjab , 152002,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hritika","family":"Rathi","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis & Imaging, Postgraduate Institute of Medical Education and Research , Sector-12, Chandigarh , 160012,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4839-5116","authenticated-orcid":false,"given":"Samiksha","family":"Lamichhane","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis & Imaging, B. 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Koirala Institute of Health Sciences , Dharan , 56700,","place":["Nepal"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,5,28]]},"reference":[{"key":"2025052810092323900_ref1","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1097\/00007632-198802000-00009","article-title":"Swelling pressure of the lumbar intervertebral discs: influence of age, spinal level, composition, and degeneration","volume":"13","author":"Urban","year":"1988","journal-title":"Spine (Phila Pa 1976)"},{"key":"2025052810092323900_ref2","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s13244-017-0584-z","article-title":"ABCs of the degenerative spine","volume":"9","author":"Kushchayev","year":"2018","journal-title":"Insights Imaging"},{"key":"2025052810092323900_ref3","doi-asserted-by":"publisher","first-page":"46","DOI":"10.25259\/IJMSR_43_2021","article-title":"Fatty disc: an unusual pattern of disc degeneration","volume":"4","author":"Choudhary","year":"2022","journal-title":"Indian J Musculoskelet Radiol"},{"key":"2025052810092323900_ref4","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1016\/j.jbiomech.2015.10.035","article-title":"Fundamental biomechanics of the spine--what we have learned in the past 25 years and future directions","volume":"49","author":"Oxland","year":"2016","journal-title":"J Biomech"},{"key":"2025052810092323900_ref5","first-page":"107","article-title":"High signal intervertebral disc in T1W MRI","volume":"6","author":"Alaee","year":"2009","journal-title":"Iran J Radiol"},{"key":"2025052810092323900_ref6","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/ar629","article-title":"Degeneration of the intervertebral disc","volume":"5","author":"Urban","year":"2003","journal-title":"Arthritis Res Ther"},{"key":"2025052810092323900_ref7","first-page":"23","article-title":"The bright intervertebral disk: an indirect sign of abnormal spinal bone marrow on T1-weighted MR images","volume":"11","author":"Castillo","year":"1990","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025052810092323900_ref8","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1148\/radiology.195.2.7724747","article-title":"Hyperintense disks on T1-weighted MR images: are they important?","volume":"195","author":"Quint","year":"1995","journal-title":"Radiology"},{"key":"2025052810092323900_ref9","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1007\/s00256-004-0843-1","article-title":"High signal intensity of intervertebral calcified disks on T1-weighted MR images resulting from fat content","volume":"34","author":"Malghem","year":"2005","journal-title":"Skeletal Radiol"},{"key":"2025052810092323900_ref10","first-page":"7","article-title":"Clinical implications of epidural fat in the spinal canal. A scanning electron microscopic study","volume":"60","author":"Reina","year":"2009","journal-title":"Acta Anaesthesiol Belg"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/5\/omaf027\/63391907\/omaf027.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/5\/omaf027\/63391907\/omaf027.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T14:09:31Z","timestamp":1748441371000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf027\/8152146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5,28]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf027","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,5]]},"published":{"date-parts":[[2025,5]]},"article-number":"omaf027"}}