{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:04:27Z","timestamp":1753877067032,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T00:00:00Z","timestamp":1748390400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Hepatic tuberculosis is a rare extrapulmonary manifestation of pulmonary or miliary tuberculosis, typically seen in immunocompromised individuals. Isolated nodular hepatic tuberculosis is exceptionally uncommon in immunocompetent individuals and often mimics other hepatic lesions such as hepatocellular carcinoma. We present a 35-year-old male who developed isolated nodular hepatic tuberculosis following high-dose dexamethasone treatment for COVID-19. Imaging and fine-needle aspiration cytology suggested hepatocellular carcinoma, prompting surgical hepatic segmentectomy. Postoperative histopathological analysis confirmed the diagnosis of isolated nodular hepatic tuberculosis. This case highlights the potential risk of hepatic tuberculosis during temporary immunosuppression caused by high-dose dexamethasone treatment for COVID-19. Our case also emphasizes the importance of utilizing preoperative PCR and histopathological examination in diagnosing hepatic tuberculosis, helping to prevent unnecessary surgical interventions.<\/jats:p>","DOI":"10.1093\/omcr\/omaf030","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T14:09:38Z","timestamp":1748441378000},"source":"Crossref","is-referenced-by-count":0,"title":["Isolated nodular hepatic tuberculosis in an immunocompetent patient following dexamethasone treatment for COVID-19"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-2595-2166","authenticated-orcid":false,"given":"Jichang","family":"Seong","sequence":"first","affiliation":[{"name":"School of Medicine, Central Asian University , 264 Milliy, bog St, Tashkent 111221,","place":["Uzbekistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Egamberdiev","family":"Dilshod","sequence":"additional","affiliation":[{"name":"Department of Hepatopancreatobiliary Surgery, Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology , Farobi Street 5-7, Tashkent 100174 ,","place":["Uzbekistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdusattorov","family":"Ravshan","sequence":"additional","affiliation":[{"name":"School of Medicine, Central Asian University , 264 Milliy, bog St, Tashkent 111221,","place":["Uzbekistan"]},{"name":"Department of Oncology, AKFA Medline University Hospital , Tashkent city, Almazar district, st. Kichik Halka Yuli, 5A Tashkent 100211 ,","place":["Uzbekistan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,5,28]]},"reference":[{"key":"2025052810093374800_ref1","first-page":"744","article-title":"Hepatobiliary tuberculosis","volume":"51","author":"Chong","year":"2010","journal-title":"Singapore Med J"},{"key":"2025052810093374800_ref2","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1186\/s12879-015-0944-6","article-title":"A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection","volume":"15","author":"Hickey","year":"2015","journal-title":"BMC Infect Dis"},{"key":"2025052810093374800_ref3","first-page":"11","article-title":"Massive primary hepatic tuberculoma mimicking hepatocellular carcinoma in an immunocompetent host","volume":"8","author":"Brookes","year":"2006","journal-title":"MedGenMed"},{"key":"2025052810093374800_ref4","first-page":"E7","article-title":"Macronodular hepatic tuberculosis necessitating hepatic resection: a diagnostic conundrum","volume":"50","author":"Vimalraj","year":"2007","journal-title":"Can J Surg"},{"key":"2025052810093374800_ref5","doi-asserted-by":"publisher","first-page":"7915084","DOI":"10.1155\/2020\/7915084","article-title":"The unexpected diagnosis of hepatic tuberculosis in an immunocompetent patient","volume":"2020","author":"Garmpis","year":"2020","journal-title":"Case Rep Surg"},{"key":"2025052810093374800_ref6","doi-asserted-by":"publisher","first-page":"e0277807","DOI":"10.1371\/journal.pone.0277807","article-title":"Tuberculosis in individuals who recovered from COVID-19: a systematic review of case reports","volume":"17","author":"Alemu","year":"2022","journal-title":"PLoS One"},{"key":"2025052810093374800_ref7","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1136\/jcp.56.11.835","article-title":"The nodular form of hepatic tuberculosis: a review with five additional new cases","volume":"56","author":"Huang","year":"2003","journal-title":"J Clin Pathol"},{"key":"2025052810093374800_ref8","doi-asserted-by":"publisher","first-page":"rjac210","DOI":"10.1093\/jscr\/rjac210","article-title":"Intestinal tuberculosis masquerading as carcinoma colon: a case report of diagnostic quandary in low-resource setting","volume":"2022","author":"Panthi","year":"2022","journal-title":"J Surg Case Rep"},{"key":"2025052810093374800_ref9","first-page":"207","article-title":"Hepatobiliary tuberculosis","volume":"27","author":"Chaudhary","year":"2014","journal-title":"Ann Gastroenterol"},{"key":"2025052810093374800_ref10","first-page":"427","article-title":"Isolated hepatic tuberculoma\u00a0- a case report","volume":"11","author":"Biswas","year":"2016","journal-title":"Iran J Pathol"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/5\/omaf030\/63391937\/omaf030.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/5\/omaf030\/63391937\/omaf030.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T14:09:40Z","timestamp":1748441380000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf030\/8152151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5,28]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf030","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2025,5]]},"published":{"date-parts":[[2025,5]]},"article-number":"omaf030"}}