{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T18:27:51Z","timestamp":1780597671821,"version":"3.54.1"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T00:00:00Z","timestamp":1748390400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Darier disease is a rare autosomal dominant inherited skin disorder, caused by mutations in the ATP2A2 gene. Oral manifestations can include mucosal lesions, salivary gland involvement, and xerostomia, that can significantly increase the risk of dental caries.<\/jats:p>\n               <jats:p>A 58-year-old female with a confirmed diagnosis of Darier disease presented with oral manifestations, including recurrent sublingual blisters, xerostomia, and carious lesions. The intraoral examination revealed white spot carious lesions and cavitated caries, particularly in the cervical areas of several teeth. Dental treatment included fluoride mouthrinse, oral hygiene instructions, and restorative care for the cavitated teeth. The patient was also advised on preventive and symptomatic measures for xerostomia.<\/jats:p>\n               <jats:p>Dentists should be aware of these potential issues and provide appropriate preventive, etiologic and symptomatic care. Regular follow-ups are essential to monitor the progression of dental lesions and manage oral health in patients with Dd.<\/jats:p>","DOI":"10.1093\/omcr\/omaf042","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T14:09:48Z","timestamp":1748441388000},"source":"Crossref","is-referenced-by-count":1,"title":["Increased caries risk in a Xerostomic patient with Darier disease: a case report of incipient and advanced carious lesions"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7008-7306","authenticated-orcid":false,"given":"Kostis","family":"Giannakopoulos","sequence":"first","affiliation":[{"name":"School of Dentistry, European University Cyprus , 6 Diogenes str, 2404 Engomi, Nicosia ,","place":["Cyprus"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1500-1896","authenticated-orcid":false,"given":"Persefoni","family":"Lambrou","sequence":"additional","affiliation":[{"name":"Scientific Collaborator, School of Dentistry, European University Cyprus , 6 Diogenes str, 2404 Engomi , Nicosia,","place":["Cyprus"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0513-5110","authenticated-orcid":false,"given":"Eleftherios G","family":"Kaklamanos","sequence":"additional","affiliation":[{"name":"School of Dentistry, European University Cyprus , 6 Diogenes str, 2404 Engomi, Nicosia ,","place":["Cyprus"]},{"name":"School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki , Central Secretariat, 1st Basement, 54124 Thessaloniki 54124 ,","place":["Greece"]},{"name":"Hamdan Bin Mohammed College of Dental Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences , Dubai 505055 ,","place":["United Arab Emirates"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1553-1870","authenticated-orcid":false,"given":"Maria Nefeli","family":"Christodoulou","sequence":"additional","affiliation":[{"name":"West Suffolk Hospital: Bury St Edmunds , GB"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,5,28]]},"reference":[{"key":"2025052810094240800_ref1","first-page":"597","article-title":"Psorospermose folliculaire vegetante","volume":"10","author":"Darier","year":"1889","journal-title":"Ann Dermatol Syphilol"},{"key":"2025052810094240800_ref2","first-page":"20f","article-title":"A case of keratosis (icthyosis) follicularis","volume":"7","author":"White","year":"1889","journal-title":"J Cutaneous Genito-Urinary 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