{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:13:53Z","timestamp":1753877633273,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T00:00:00Z","timestamp":1750982400000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Calciphylaxis is an uncommon yet highly severe condition characterized by systemic medial calcification of arterioles, leading to ischemia and subsequent tissue necrosis. we report the case of a 29\u00a0year-old female suffering from primary hyperoxaluria type 1 and end-stage renal disease, Developed multiple painful ulcerations on her legs, initially believed to be due to cutaneous oxalosis. However, pathology findings revealed calciphylaxis. The association calciphylaxis and hyperoxaluria is rare, making this case unique. and she was treated with medical therapy, high-flow oxygen therapy and advanced wound dressings to facilitate granulation tissue formation and optimize ulcer healing, and daily hemodialysis with a low-calcium dialysate.<\/jats:p>","DOI":"10.1093\/omcr\/omaf068","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T04:57:56Z","timestamp":1751000276000},"source":"Crossref","is-referenced-by-count":0,"title":["Chronic leg ulcers in a patient with Hyperoxaluria type 1: a rare and challenging diagnosis"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2955-7513","authenticated-orcid":false,"given":"Soukayna","family":"Kabbou","sequence":"first","affiliation":[{"name":"Dermatology Department, University hospital center Mohammed VI , Tangier 40000 ,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ouiam","family":"Eljouari","sequence":"additional","affiliation":[{"name":"Dermatology Department, University hospital center Mohammed VI , Tangier 40000 ,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salim","family":"Gallouj","sequence":"additional","affiliation":[{"name":"Dermatology Department, University hospital center Mohammed VI , Tangier 40000 ,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,27]]},"reference":[{"key":"2025062806571546300_ref1","first-page":"424","article-title":"Calculs multiples chez l\u2019enfant","volume":"20","author":"Lepoutre","year":"1925","journal-title":"J Urol"},{"key":"2025062806571546300_ref2","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/0014-5793(86)80563-4","article-title":"Peroxisomal alanine: glyoxylate aminotransferase deficiency in primary hyperoxaluria type 1","volume":"201","author":"Danpure","year":"1986","journal-title":"FEBS Lett"},{"key":"2025062806571546300_ref3","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1016\/j.mayocp.2016.06.025","article-title":"Survival, risk factors, and effect of treatment in 101 patients with calci- phylaxis","volume":"91","author":"McCarthy","year":"2016","journal-title":"Mayo Clin Proc"},{"key":"2025062806571546300_ref4","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1053\/ajkd.1998.v32.pm9740153","article-title":"Cutaneous necrosis from calcific uremic arteriolopathy","volume":"32","author":"Coates","year":"1998","journal-title":"Am J Kidney Dis"},{"key":"2025062806571546300_ref5","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1111\/ijd.13622","article-title":"Early clinical presentations and progression of calci- phylaxis","volume":"56","author":"Ghosh","year":"2017","journal-title":"Int J Dermatol"},{"key":"2025062806571546300_ref6","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1097\/MNH.0000000000000328","article-title":"Calciphylaxis","volume":"26","author":"Nigwekar","year":"2017","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"2025062806571546300_ref7","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1093\/ckj\/sfz190","article-title":"Calciphylaxis or vascular oxalosis?","volume":"14","author":"El-Saygeh","year":"2020","journal-title":"Clin Kidney J"},{"key":"2025062806571546300_ref8","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/pmj.77.911.557","article-title":"Calciphylaxis","volume":"77","author":"Mathur","year":"2001","journal-title":"Post- grad Med J"},{"key":"2025062806571546300_ref9","first-page":"676","article-title":"Hyperbaric oxygen therapy for calcific uremic arteriolopa- thy: a case series","volume":"15","author":"Basile","year":"2002","journal-title":"J Nephrol"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/6\/omaf068\/63596106\/omaf068.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/6\/omaf068\/63596106\/omaf068.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T10:57:25Z","timestamp":1751108245000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf068\/8175744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6,27]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf068","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2025,6]]},"published":{"date-parts":[[2025,6]]},"article-number":"omaf068"}}