{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T18:52:10Z","timestamp":1754160730176,"version":"3.41.2"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Large extraluminal gastrointestinal stromal tumours (GISTs) are rare, with varied presentations and patient profiles. This report discusses the case of a 22-year-old female presenting with a 4-month history of lower abdominal pain, weight loss, and recurrent urinary tract infections. Imaging revealed a large intra-abdominal mass (9.3 \u00d7 15.3 \u00d7 18.9\u00a0cm) originating from the stomach, extending into the pelvis, and compressing adjacent structures. During surgery, the mass was found to arise from the lesser curvature of the stomach and adhered to the transverse colon, with non-adherent extension into the pelvis and compression of adjacent organs. A gastric wedge resection and transverse colectomy were performed with aim of achieving a R0 resection. Histopathological analysis confirmed a GIST and positive resection margins. A plan for adjuvant imatinib was initiated in accordance with the European Society for Medical Oncology (ESMO) guidelines. This article details the challenges faced in the management of such a rare presentation and highlights similar reports.<\/jats:p>","DOI":"10.1093\/omcr\/omaf093","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T14:47:54Z","timestamp":1752504474000},"source":"Crossref","is-referenced-by-count":0,"title":["Massive Extraluminal gastrointestinal stromal tumour with pelvic extension: case report and mini-review of the literature"],"prefix":"10.1093","volume":"2025","author":[{"given":"Yasir","family":"Alshareefy","sequence":"first","affiliation":[{"name":"St James's Hospital Dublin, James's Street, Dublin 8, D08NHY1 ,","place":["Ireland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Alshareefy","sequence":"additional","affiliation":[{"name":"Medcare Dr. Saeed Al-Shaikh Gastroenterology and Obesity Centre , Sheikh Zayed Road, SMJ Building, PO Box 215565, Dubai ,","place":["United Arab Emirates"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"2025072710515337100_ref1","doi-asserted-by":"publisher","first-page":"694","DOI":"10.3390\/jpm11080694","article-title":"Gastrointestinal stromal tumors\u2014a mini review","volume":"11","author":"Gheorghe","year":"2021","journal-title":"J Pers Med"},{"key":"2025072710515337100_ref2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2020\/6590307","article-title":"A huge pelvic-abdominal malignant GIST tumour in a patient with Neurofibromatosis type 1: case report and literature review","volume":"2020","author":"Omar","year":"2020","journal-title":"Case Rep Oncol Med"},{"key":"2025072710515337100_ref3","doi-asserted-by":"publisher","first-page":"144","DOI":"10.21037\/jgo.2018.08.20","article-title":"Gastrointestinal stromal tumors: a comprehensive review","volume":"10","author":"Parab","year":"2019","journal-title":"J Gastrointest Oncol"},{"key":"2025072710515337100_ref4","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/j.annonc.2021.09.005","article-title":"Gastrointestinal stromal tumours: ESMO\u2013EURACAN\u2013GENTURIS clinical practice guidelines for diagnosis, treatment and follow-up","volume":"33","author":"Casali","year":"2021","journal-title":"Ann Oncol"},{"key":"2025072710515337100_ref5","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjaa355","article-title":"Massive bleeding of a jejunal gastrointestinal stromal tumour: a rare case of a life-threatening presentation","volume":"2020","author":"Mahmoud","year":"2020","journal-title":"J Surg Case Rep"},{"key":"2025072710515337100_ref6","doi-asserted-by":"publisher","first-page":"99","DOI":"10.5152\/ucd.2015.2877","article-title":"Spontaneous rupture of extraluminal jejunal gastrointestinal stromal tumor causing acute abdomen and hemoperitoneum","volume":"31","author":"Attaallah","year":"2015","journal-title":"Turk J Surg"},{"key":"2025072710515337100_ref7","doi-asserted-by":"publisher","first-page":"2928","DOI":"10.3748\/wjg.14.2928","article-title":"A ruptured large extraluminal ileal gastrointestinal stromal tumor causing hemoperitoneum","volume":"14","author":"Hirasaki","year":"2008","journal-title":"World J Gastroenterol"},{"key":"2025072710515337100_ref8","doi-asserted-by":"publisher","first-page":"e18103","DOI":"10.1097\/md.0000000000018103","article-title":"A rare case of extraluminal gastrointestinal stromal tumor of the ileum presenting with lower urinary tract symptoms","volume":"98","author":"Yu","year":"2019","journal-title":"Medicine"},{"key":"2025072710515337100_ref9","doi-asserted-by":"publisher","first-page":"e19885","DOI":"10.1097\/md.0000000000019885","article-title":"Characteristic of extra luminal gastric stromal tumor arising from the lesser curvature of the stomach","volume":"99","author":"Wang","year":"2020","journal-title":"Medicine"},{"key":"2025072710515337100_ref10","doi-asserted-by":"publisher","first-page":"7525","DOI":"10.1186\/1757-1626-2-7525","article-title":"Extra luminal colonic gastrointestinal stromal tumor: a case report","volume":"2","author":"Masoodi","year":"2009","journal-title":"Cases J"},{"key":"2025072710515337100_ref11","doi-asserted-by":"publisher","first-page":"583","DOI":"10.4253\/wjge.v9.i12.583","article-title":"Endoscopic ultrasound-guided fine-needle aspiration for diagnosing a rare extraluminal duodenal gastrointestinal tumor","volume":"9","author":"Hayashi","year":"2017","journal-title":"World J Gastrointest Endosc"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/7\/omaf093\/63748907\/omaf093.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/7\/omaf093\/63748907\/omaf093.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T14:52:00Z","timestamp":1753627920000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf093\/8200189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7,14]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf093","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2025,7]]},"published":{"date-parts":[[2025,7]]},"article-number":"omaf093"}}