{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T18:52:09Z","timestamp":1754160729057,"version":"3.41.2"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Eccrine spiradenoma is one of the rarest benign adnexal tumors. Its clinical presentation is nonspecific, often necessitating a differential diagnosis with other benign cutaneous tumors, highlighting the crucial role of histological examination. The literature provides limited descriptions of this tumor, particularly in elderly patients, emphasizing the significance of our case. Our patient, a 61-year-old man with no significant medical history, presented with a painless cutaneous lesion on his back that had been progressively enlarging over six years. Clinical examination revealed a subcutaneous nodule with a firm consistency, measuring 2\u00a0cm in its largest dimension. Complete excision of the lesion was performed for pathological examination. Clinical findings, combined with histology and immunohistochemistry, confirmed the diagnosis of eccrine spiradenoma. This is a benign tumor of the eccrine sweat glands, rarely reported in the literature, typically presenting as a solitary nodule, sometimes multiple, with its primary clinical feature being paroxysmal tenderness. Early and complete surgical excision serves both diagnostic and therapeutic purposes. In addition to its rarity, the occurrence in an elderly patient and its painless nature make our publication particularly noteworthy. This article reports a case of eccrine spiradenoma identified in an elderly patient initially suspected of having an epidermoid cyst, underscoring the importance of histopathological examination for any cutaneous tumor.<\/jats:p>","DOI":"10.1093\/omcr\/omaf103","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T14:47:38Z","timestamp":1752504458000},"source":"Crossref","is-referenced-by-count":0,"title":["A case of an eccrine spiradenoma in an elderly patient mimicking an epidermoid cyst"],"prefix":"10.1093","volume":"2025","author":[{"given":"Meryeme","family":"Boutaarourt","sequence":"first","affiliation":[{"name":"Department of Dermatology-Venereology, Mohamed VI University Hospital , M3MF+GCG, 90100 , La Nouvelle Ville Ibn Batouta, Tangier,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy , M3MF+GCG, 90100, La Nouvelle Ville Ibn Batouta, Tangier ,","place":["Morocco"]},{"name":"Abdelmalek Essaadi University , 93030, BP2117 - Av. 9 Avril, Quartier M'hanneche II, Tetouan,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ouiame","family":"El Jouari","sequence":"additional","affiliation":[{"name":"Department of Dermatology-Venereology, Mohamed VI University Hospital , M3MF+GCG, 90100 , La Nouvelle Ville Ibn Batouta, Tangier,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy , M3MF+GCG, 90100, La Nouvelle Ville Ibn Batouta, Tangier ,","place":["Morocco"]},{"name":"Abdelmalek Essaadi University , 93030, BP2117 - Av. 9 Avril, Quartier M'hanneche II, Tetouan,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salim","family":"Gallouj","sequence":"additional","affiliation":[{"name":"Department of Dermatology-Venereology, Mohamed VI University Hospital , M3MF+GCG, 90100 , La Nouvelle Ville Ibn Batouta, Tangier,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy , M3MF+GCG, 90100, La Nouvelle Ville Ibn Batouta, Tangier ,","place":["Morocco"]},{"name":"Abdelmalek Essaadi University , 93030, BP2117 - Av. 9 Avril, Quartier M'hanneche II, Tetouan,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"2025072710513975500_ref1","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/s00238-015-1103-4","article-title":"A rare case of eccrine spiradenoma-treatment and management","volume":"39","author":"Dhua","year":"2016","journal-title":"Eur J Plast Surg"},{"key":"2025072710513975500_ref2","doi-asserted-by":"publisher","first-page":"519","DOI":"10.5021\/ad.2017.29.4.519","article-title":"A case of eccrine Spiradenoma: a rarely seen soft tissue tumor on the extensor surface of arm","volume":"29","author":"Son","year":"2017","journal-title":"Ann Dermatol"},{"key":"2025072710513975500_ref3","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1136\/jmg.2007.056127","article-title":"CYLD mutations in familial skin appendage tumours","volume":"45","author":"Saggar","year":"2008","journal-title":"J Med Genet"},{"key":"2025072710513975500_ref4","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1111\/his.14441","article-title":"Molecular pathology of skin adnexal tumours","volume":"80","author":"Plotzke","year":"2022","journal-title":"Histopathology."},{"key":"2025072710513975500_ref5","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1016\/0278-2391(88)90061-4","article-title":"Eccrine spiradenoma: report of a case","volume":"46","author":"Yun","year":"1988","journal-title":"J Oral Maxillofac Surg"},{"key":"2025072710513975500_ref6","doi-asserted-by":"publisher","first-page":"00390","DOI":"10.15406\/mojor.2018.10.00390","article-title":"Eccrine spiradenoma as a differential diagnosis in chronic soft tissue lesions of the foot. MOJ Orthop","volume":"10","author":"Almeida","year":"2018","journal-title":"Rheumatol."},{"volume-title":"Spiradenoma. StatPearls","year":"2022","author":"Miceli","key":"2025072710513975500_ref7"},{"key":"2025072710513975500_ref8","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.3892\/etm.2014.1906","article-title":"Differential diagnosis of eccrine spiradenoma: a case report","volume":"8","author":"Zheng","year":"2014","journal-title":"Exp Ther Med"},{"key":"2025072710513975500_ref9","doi-asserted-by":"publisher","first-page":"2045","DOI":"10.3390\/jcm12052045","article-title":"Spiradenocarcinoma: SEER study of epidemiology, survival, and treatment options","volume":"12","author":"Martineau","year":"2023","journal-title":"J Clin Med"},{"key":"2025072710513975500_ref10","doi-asserted-by":"publisher","first-page":"591","DOI":"10.5858\/2002-126-0591-MES","article-title":"Malignant eccrine Spiradenoma","volume":"126","author":"Mirza","year":"2002","journal-title":"Arch Pathol Lab Med"},{"key":"2025072710513975500_ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2016.09.038","article-title":"Transformation maligne d'un spirad\u00e9nome eccrine","volume-title":"Ann Dermatol V\u00e9n\u00e9r\u00e9ol. Mars","year":"2017"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/7\/omaf103\/63748829\/omaf103.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/7\/omaf103\/63748829\/omaf103.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T14:51:44Z","timestamp":1753627904000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf103\/8200178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7,14]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf103","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2025,7]]},"published":{"date-parts":[[2025,7]]},"article-number":"omaf103"}}