{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:14:06Z","timestamp":1783433646985,"version":"3.54.6"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Multivalvular infective endocarditis (MIE) is an uncommon condition associated with increased morbidity and mortality compared to single-valve involvement. We present the case of a young patient with a bicuspid aortic valve and MIE affecting both the aortic and mitral valves, caused by Streptococcus pluranimalium. Timely diagnosis, targeted antibiotic therapy, and surgical intervention with dual-valve replacement led to a favorable clinical outcome. This case highlights the importance of considering the diagnosis of infective endocarditis in young patients presenting with fever and constitutional symptoms without an apparent cause and initiating the investigation of an underlying congenital heart disease. It also highlights that uncommon pathogens may be etiological agents of infective endocarditis in patients with predisposing valvular abnormalities.<\/jats:p>","DOI":"10.1093\/omcr\/omaf156","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T20:14:23Z","timestamp":1758312863000},"source":"Crossref","is-referenced-by-count":3,"title":["Multivalvular infective endocarditis due to <i>streptococcus pluranimalium<\/i> in a young patient with bicuspid aortic valve"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-4060-7648","authenticated-orcid":false,"given":"Jos\u00e9 Emmanuel","family":"Z\u00fa\u00f1iga-Espinosa","sequence":"first","affiliation":[{"name":"Division of Postgraduate Studies, Universidad Nacional Aut\u00f3noma de M\u00e9xico , Circuito de Posgrados s\/n, Ciudad Universitaria, Coyoac\u00e1n, CP 04510, Mexico City ,","place":["Mexico"]},{"name":"Internal Medicine Department, Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro M\u00e9dico Nacional \u201cLa Raza\u201d, Instituto Mexicano del Seguro Social , Seris y Zahachila s\/n, Colonia La Raza, Azcapotzalco, CP 02990, Mexico City ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6735-0070","authenticated-orcid":false,"given":"Ana Lilia","family":"Peralta-Amaro","sequence":"additional","affiliation":[{"name":"Division of Postgraduate Studies, Universidad Nacional Aut\u00f3noma de M\u00e9xico , Circuito de Posgrados s\/n, Ciudad Universitaria, Coyoac\u00e1n, CP 04510, Mexico City ,","place":["Mexico"]},{"name":"Internal Medicine Department, Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro M\u00e9dico Nacional \u201cLa Raza\u201d, Instituto Mexicano del Seguro Social , Seris y Zahachila s\/n, Colonia La Raza, Azcapotzalco, CP 02990, Mexico City 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Central Sur de Alta Especialidad, Petr\u00f3leos Mexicanos , Anillo Perif\u00e9rico No. 4091, Fuentes del Pedregal, Tlalpan, CP 14140, Mexico City ,","place":["Mexico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9521-0018","authenticated-orcid":false,"given":"Mariel Ivonne","family":"Garc\u00eda-Santiago","sequence":"additional","affiliation":[{"name":"Division of Postgraduate Studies, Universidad Nacional Aut\u00f3noma de M\u00e9xico , Circuito de Posgrados s\/n, Ciudad Universitaria, Coyoac\u00e1n, CP 04510, Mexico City ,","place":["Mexico"]},{"name":"Internal Medicine Department, Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro M\u00e9dico Nacional \u201cLa Raza\u201d, Instituto Mexicano del Seguro Social , Seris y Zahachila s\/n, Colonia La Raza, Azcapotzalco, CP 02990, Mexico City 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