{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:56:27Z","timestamp":1760648187058,"version":"3.44.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:00:00Z","timestamp":1759017600000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Varicella-zoster virus (VZV) reactivation in immunocompromised patients may present atypically, including with severe gastrointestinal involvement. We present a case of a 36-year-old male with ileocolic Crohn\u2019s disease, who, following Infliximab (IFX) therapy, developed severe gastrointestinal symptoms. Subsequent investigations confirmed a disseminated VZV infection with esophagogastric and duodenal involvement. Our case highlights the crucial need for heightened clinical awareness regarding unusual VZV presentations in immunocompromised patients, especially those receiving TNF- \u03b1 inhibitors such as Infliximab, known to increase the risk of VZV reactivation. Given the potentially high mortality rate (approximately 40%) associated with gastrointestinal VZV involvement, prompt and aggressive antiviral treatment is imperative.<\/jats:p>","DOI":"10.1093\/omcr\/omaf171","type":"journal-article","created":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:42:19Z","timestamp":1759048939000},"source":"Crossref","is-referenced-by-count":1,"title":["Gastrointestinal herpes zoster in a patient on infliximab: a case report"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1536-913X","authenticated-orcid":false,"given":"Imane","family":"El Hamraoui","sequence":"first","affiliation":[{"name":"Department of Gastroentero-Hepatology and Proctology \u201cMedecine B\u201d, Ibn Sina University Hospital, Mohammed V University , Abderrahim Bouabid avenue, Souissi, Rabat 10100 ,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Houda","family":"El Hiouy","sequence":"additional","affiliation":[{"name":"Department of Gastroentero-Hepatology and Proctology \u201cMedecine B\u201d, Ibn Sina University Hospital, Mohammed V University , Abderrahim Bouabid avenue, Souissi, Rabat 10100 ,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salma","family":"Mechhor","sequence":"additional","affiliation":[{"name":"Department of Gastroentero-Hepatology and Proctology \u201cMedecine B\u201d, Ibn Sina University Hospital, Mohammed V University , Abderrahim Bouabid avenue, Souissi, Rabat 10100 ,","place":["Morocco"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manal","family":"Cherkaoui El Malki","sequence":"additional","affiliation":[{"name":"Department of Gastroentero-Hepatology and Proctology \u201cMedecine B\u201d, Ibn Sina University Hospital, Mohammed V University , Abderrahim Bouabid avenue, Souissi, Rabat 10100 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