{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:08:32Z","timestamp":1791666512272,"version":"4.3.4"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Ommaya reservoirs, commonly used in the management of intrathecal chemotherapy, can sometimes lead to complications, including cerebral edema and porencephaly. We present the case of a 65-year-old woman with a suprasellar craniopharyngioma who developed these rare complications after the placement of an Ommaya reservoir. The initial CT and MRI findings revealed a hypodense area in the right frontal lobe along the Ommaya catheter, consistent with a vasogenic edema. Laboratory work-ups, including inflammatory markers, were normal, and the patient did not exhibit fever. This case highlights the need for clinicians to be aware of this potential complication when managing patients with Ommaya reservoirs.<\/jats:p>","DOI":"10.1093\/omcr\/omaf195","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T11:42:40Z","timestamp":1756467760000},"source":"Crossref","is-referenced-by-count":1,"title":["Beyond infection: Ommaya reservoir-induced vasogenic edema and reversible leukoencephalopathy"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6382-9906","authenticated-orcid":false,"given":"Mohamed","family":"Fadil","sequence":"first","affiliation":[{"name":"Radiology department, Mohamed V Military Hospital , Av. Abderrahim Bouabid, Rabat 10112 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imane","family":"Mohammadine","sequence":"additional","affiliation":[{"name":"Radiology department, Mohamed V Military Hospital , Av. Abderrahim Bouabid, Rabat 10112 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachida","family":"Saouab","sequence":"additional","affiliation":[{"name":"Radiology department, Mohamed V Military Hospital , Av. Abderrahim Bouabid, Rabat 10112 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"En-Nouali","sequence":"additional","affiliation":[{"name":"Radiology department, Mohamed V Military Hospital , Av. Abderrahim Bouabid, Rabat 10112 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamal","family":"El Fenni","sequence":"additional","affiliation":[{"name":"Radiology department, Mohamed V Military Hospital , Av. Abderrahim Bouabid, Rabat 10112 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zakariya","family":"Toufga","sequence":"additional","affiliation":[{"name":"Radiology department, Mohamed V Military Hospital , Av. Abderrahim Bouabid, Rabat 10112 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,10,22]]},"reference":[{"key":"2025102212545690500_ref1","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1007\/s002340050718","article-title":"Leukoencephalopathy complicating an Ommaya reservoir and chemotherapy","volume":"41","author":"Stone","year":"1999","journal-title":"Neuroradiology"},{"key":"2025102212545690500_ref2","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1177\/19418744221106313","article-title":"Intrathecal methotrexate toxicity resulting in brain death due to generalized cerebral edema: a case report","volume":"12","author":"Pang","year":"2022","journal-title":"Neurohospitalist"},{"key":"2025102212545690500_ref3","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1007\/BF01850981","article-title":"Transient focal leukoencephalopathy following intraventricular methotrexate and cytarabine. A complication of the Ommaya reservoir: case report and review of the literature","volume":"6","author":"Colamaria","year":"1990","journal-title":"Childs Nerv Syst"},{"key":"2025102212545690500_ref4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.3892\/mco.2020.2032","article-title":"Troubleshooting an unusual complication following intrathecal chemotherapy delivered via Ommaya catheter: a case report","volume":"13","author":"Mauler","year":"2020","journal-title":"Mol Clin Oncol"},{"key":"2025102212545690500_ref5","doi-asserted-by":"publisher","first-page":"954","DOI":"10.12659\/AJCR.915632","article-title":"Methotrexate-induced subacute neurotoxicity surrounding an Ommaya reservoir in a patient with lymphoma","volume":"20","author":"Oarbeascoa","year":"2019","journal-title":"Am J Case Rep"},{"key":"2025102212545690500_ref6","doi-asserted-by":"publisher","first-page":"694","DOI":"10.3171\/jns.1997.87.5.0694","article-title":"Complications associated with intraventricular chemotherapy","volume":"87","author":"Chamberlain","year":"1997","journal-title":"J Neurosurg"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/10\/omaf195\/64858026\/omaf195.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/10\/omaf195\/64858026\/omaf195.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T16:55:04Z","timestamp":1761152104000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf195\/8297188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":6,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10,21]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf195","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,10]]},"published":{"date-parts":[[2025,10]]},"article-number":"omaf195"}}