{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T20:54:02Z","timestamp":1780520042302,"version":"3.54.1"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pure red blood cell aplasia (PRCA) is a rare complication of major ABO-incompatible hematopoietic stem cell transplantation (HSCT), characterized by severe anemia due to impaired erythropoiesis. We report the case of 52\u00a0year old man with chronic myeloid leukemia who developed refractory PRCA four months post transplant. The patient was unresponsive to multiple immunosuppressive agents but showed marked hematologic recovery following ten sessions of plasma exchange (PEX) over five weeks. Hemoglobine level rose from 6\u00a0g\/Dl to 16\u00a0g\/dL, eliminating the need for further transfusions. This report highlights a case of refractory PRCA successfully treated with PEX, underscoring its potential efficacy and the need for further research to establish treatment guidelines.<\/jats:p>","DOI":"10.1093\/omcr\/omaf225","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T11:58:15Z","timestamp":1758974295000},"source":"Crossref","is-referenced-by-count":1,"title":["Plasma exchange as an effective treatment for refractory pure red cell aplasia post-ABO-incompatible hematopoietic stem cell transplantation: a rare complication"],"prefix":"10.1093","volume":"2025","author":[{"given":"Asaad A","family":"Khalaf","sequence":"first","affiliation":[{"name":"Consultant hematologist, Basrah Health Directorate , Basrah ,","place":["Iraq"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Al Farttoosi","sequence":"additional","affiliation":[{"name":"College of Medicine, University of Basrah , Basrah ,","place":["Iraq"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6259-1045","authenticated-orcid":false,"given":"Sajjad Ghanim","family":"Al-Badri","sequence":"additional","affiliation":[{"name":"College of Medicine, University of Warith Al-Anbiyaa , Karbala ,","place":["Iraq"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3722-702X","authenticated-orcid":false,"given":"Abbas Hamza","family":"Abbas","sequence":"additional","affiliation":[{"name":"College of Medicine, University of Basrah , Basrah ,","place":["Iraq"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riyam Mudheher Nabbat","family":"Al-Ajrash","sequence":"additional","affiliation":[{"name":"AL-Yarmook teaching hospital , Baghdad ,","place":["Iraq"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Shamil","family":"Hashim","sequence":"additional","affiliation":[{"name":"University of Baghdad, College of Medicine , Baghdad ,","place":["Iraq"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaryab","family":"Bacha","sequence":"additional","affiliation":[{"name":"Khyber Medical College , Peshawar ,","place":["Pakistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"2025112607521305800_ref1","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1002\/jca.22041","article-title":"Successful treatment of pure red cell aplasia using therapeutic plasma exchange after ABO-incompatible hematopoietic stem cell transplant","volume":"38","author":"Vivero","year":"2023","journal-title":"J Clin Apher"},{"key":"2025112607521305800_ref2","doi-asserted-by":"publisher","first-page":"585628","DOI":"10.3389\/fmed.2020.585628","article-title":"Antigen-specific Immunoadsorption with the Glycosorb\u00ae ABO Immunoadsorption system as a novel treatment modality in pure red cell 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