{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:57:08Z","timestamp":1790377028286,"version":"4.1.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Primary duodenal cancer is very rare, accounting for approximately 0.3% of all gastrointestinal cancers. Duodenal cancer is most often located in the descending portion of the duodenum, and cancer of the bulb is exceedingly rare. Additionally, most types of duodenal cancers are histologically differentiated adenocarcinomas, and signet ring cell carcinoma of the duodenum is extremely rare. Since most cases of signet ring cell carcinoma of the duodenum are discovered at an advanced stage, endoscopic treatment is seldom indicated. Here, we report a case of a 72-year-old woman in whom endoscopic treatment was performed for early signet ring cell carcinoma of the duodenum localized in the duodenal bulb, with achievement of curative resection. This is a valuable report of endoscopic curative resection of signet ring cell carcinoma of the duodenal bulb.<\/jats:p>","DOI":"10.1093\/omcr\/omaf227","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T12:26:31Z","timestamp":1759235191000},"source":"Crossref","is-referenced-by-count":9,"title":["Endoscopic resection of signet ring cell carcinoma of the duodenal bulb"],"prefix":"10.1093","volume":"2025","author":[{"given":"Ryosuke","family":"Oura","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center , 2-1-50 Minamikoshigaya, Koshigaya City , Saitama 343-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2203-9443","authenticated-orcid":false,"given":"Yasumi","family":"Katayama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center , 2-1-50 Minamikoshigaya, Koshigaya City , Saitama 343-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yo","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center , 2-1-50 Minamikoshigaya, Koshigaya City , Saitama 343-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuhiro","family":"Kobori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center , 2-1-50 Minamikoshigaya, Koshigaya City , Saitama 343-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichi","family":"Ban","sequence":"additional","affiliation":[{"name":"Department of Pathology, Dokkyo Medical University Saitama Medical Center , Koshigaya City ,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Tamano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center , 2-1-50 Minamikoshigaya, Koshigaya City , Saitama 343-8555,","place":["Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"key":"2025112607525018400_ref1","doi-asserted-by":"publisher","first-page":"165","DOI":"10.2147\/IMCRJ.S256107","article-title":"Primary duodenal adenocarcinoma: uncommon tumor, uncommon presentation. A case report and review of the literature","volume":"13","author":"Khanal","year":"2020","journal-title":"Int Med Case Rep J"},{"key":"2025112607525018400_ref2","doi-asserted-by":"publisher","first-page":"e79996","DOI":"10.7759\/cureus.79996","article-title":"Duodenal bulb adenocarcinoma: a case report","volume":"17","author":"Kloub","year":"2025","journal-title":"Cureus"},{"key":"2025112607525018400_ref3","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1038\/modpathol.2016.174","article-title":"Non-ampullary-duodenal carcinomas: clinicopathologic analysis of 47 cases and comparison with ampullary and pancreatic adenocarcinomas","volume":"30","author":"Xue","year":"2017","journal-title":"Mod Pathol"},{"key":"2025112607525018400_ref4","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s40792-017-0287-1","article-title":"Poorly differentiated adenocarcinoma with signet-ring cells in duodenal papilla: a case report","volume":"3","author":"Ushida","year":"2017","journal-title":"Surg Case Rep"},{"key":"2025112607525018400_ref5","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s12876-022-02267-0","article-title":"Signet-ring cell carcinoma of the duodenal bulb presenting with gastrointestinal hemorrhage: a case report and literature review","volume":"22","author":"Ye","year":"2022","journal-title":"BMC Gastroenterol"},{"key":"2025112607525018400_ref6","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1007\/s12328-020-01173-w","article-title":"Successful endoscopic mucosal resection for non-ampullary duodenal signet-ring cell carcinoma","volume":"13","author":"Okamoto","year":"2020","journal-title":"Clin J Gastroenterol"},{"key":"2025112607525018400_ref7","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/den.14110","article-title":"Endoscopic treatment for duodenal neoplasms","volume":"34","author":"Hoteya","year":"2022","journal-title":"Dig Endosc"},{"key":"2025112607525018400_ref8","doi-asserted-by":"publisher","first-page":"279","DOI":"10.5152\/tjg.2020.181031","article-title":"Adenocarcinoma coexisting with signet ring cell carcinoma in nonampullary duodenum","volume":"31","author":"Lee","year":"2020","journal-title":"Turk J Gastroenterol"},{"key":"2025112607525018400_ref9","first-page":"311","article-title":"A rare case of signet-ring cell carcinoma associated with poorly differentiated adenocarcinoma of the non-ampullary duodenum","volume":"59","author":"Carasca","year":"2018","journal-title":"Romanian J Morphol Embryol"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/11\/omaf227\/65549617\/omaf227.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/11\/omaf227\/65549617\/omaf227.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T12:52:56Z","timestamp":1764161576000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf227\/8343270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,26]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf227","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,11]]},"published":{"date-parts":[[2025,11]]},"article-number":"omaf227"}}