{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:10:31Z","timestamp":1793085031666,"version":"4.5.0"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T00:00:00Z","timestamp":1764115200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pierre Robin sequence (PRS) is a rare congenital abnormality that may complicate serious circumstances in infants. We report a very rare case of PRS in a five-day-old Afghan girl, accompanied by patent ductus arteriosus (PDA), severe persistent pulmonary hypertension of the newborn (PPHN), perinatal asphyxia, sepsis, and low birth weight. The integration of these comorbidities with PRS makes the case noteworthy. The infant was initially admitted due to perinatal asphyxia and hypothermia and, was discharged in stable condition the next day. On the fifth day of life, she was readmitted with a diagnosis of PDA, severe PPHN, and sepsis, and received treatment for these conditions. Finally, the newborn died from cardiopulmonary arrest resulting from respiratory failure caused by severe airway obstruction and comorbidities. PRS may predispose the neonate to PDA, PPHN, perinatal asphyxia and infection. Consequently, it is important to treat coexisting morbidities that worsen prognosis, especially in resource-limited settings.<\/jats:p>","DOI":"10.1093\/omcr\/omaf235","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T11:31:26Z","timestamp":1759750286000},"source":"Crossref","is-referenced-by-count":2,"title":["Very rare combination of Pierre Robin sequence with patent ductus arteriosus, severe persistent pulmonary hypertension, and sepsis in an Afghan neonate: a case report and literature review"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6109-5264","authenticated-orcid":false,"given":"Mansoor","family":"Aslamzai","sequence":"first","affiliation":[{"name":"Department of Neonatology, Kabul University of Medical Sciences \u201cAbu Ali Ibni Sina\u201d (KUMS) , 3rd district, Kabul 1003 ,","place":["Afghanistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7308-6859","authenticated-orcid":false,"given":"Turyalai","family":"Hakimi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Surgery , KUMS, 3rd district, Kabul 1003 ,","place":["Afghanistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Hakim","family":"Mukhlis","sequence":"additional","affiliation":[{"name":"Teaching Assistant, Department of Neonatology , KUMS, 3rd district, Kabul 1003 ,","place":["Afghanistan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esrar Ahmad","family":"Mansoori","sequence":"additional","affiliation":[{"name":"Student at the Faculty of Medicine , KUMS, 3rd district, Kabul 1003 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