{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T07:56:07Z","timestamp":1766735767084,"version":"3.48.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Autoimmune hepatitis (AIH) is a chronic inflammatory disease that results from autoantibody mediated hepatocyte injury. Given its immune-mediated mechanism, it is more likely to present with other autoimmune conditions, particularly involving thyroid gland. In patients presenting with both Graves\u2019 disease and hepatitis, the diagnostic challenge is to determine the cause of elevated liver enzymes. We present an 11-year-old girl with acute liver cell failure and cholestasis in a setting of untreated hyperthyroidism. She was diagnosed to have Graves\u2019 disease with AIH and primary sclerosing cholangitis. She underwent radioactive iodine ablation of thyroid gland and is currently responding well on steroid, azathioprine, and thyroid replacement therapy.<\/jats:p>","DOI":"10.1093\/omcr\/omaf261","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T13:13:33Z","timestamp":1761830013000},"source":"Crossref","is-referenced-by-count":0,"title":["Graves\u2019 disease with autoimmune hepatitis and primary Sclerosing cholangitis: an overlap syndrome"],"prefix":"10.1093","volume":"2025","author":[{"given":"L K","family":"Pragathi","sequence":"first","affiliation":[{"name":"Department of Pediatric Gastroenterology and Hepatology, Bai Jerbai Wadia Hospital for Children, Acharya Dhonde Marg, Parel , Mumbai, MH 400012 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7249-7955","authenticated-orcid":false,"given":"Dhruv","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Hepatology, Bai Jerbai Wadia Hospital for Children, Acharya Dhonde Marg, Parel , Mumbai, MH 400012 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivangi","family":"Tetarbe","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Hepatology, Bai Jerbai Wadia Hospital for Children, Acharya Dhonde Marg, Parel , Mumbai, MH 400012 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudha Rao","family":"Chandrashekhar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Endocrinology, Bai Jerbai Wadia Hospital for Children, Acharya Dhonde Marg, Parel , Mumbai, MH 400012 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ira","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology and Hepatology, Bai Jerbai Wadia Hospital for Children, Acharya Dhonde Marg, Parel , Mumbai, MH 400012 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"2025122602495790200_ref1","doi-asserted-by":"publisher","first-page":"e4647","DOI":"10.7759\/cureus.4647","article-title":"Successful Management of Patients with Co-existent graves' disease and autoimmune hepatitis","volume":"11","author":"Rana","year":"2019","journal-title":"Cureus."},{"key":"2025122602495790200_ref2","doi-asserted-by":"publisher","first-page":"2139","DOI":"10.2169\/internalmedicine.8417-16","article-title":"Histological changes in autoimmune hepatitis with graves' disease: a child case report","volume":"56","author":"Yamada","year":"2017","journal-title":"Intern Med"},{"key":"2025122602495790200_ref3","doi-asserted-by":"publisher","first-page":"11795514221074672","DOI":"10.1177\/11795514221074672","article-title":"Hyperthyroidism and liver dysfunction: a review of a common 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Coincidence or combined pathogenesis?","volume":"10","author":"Janssen","year":"1998","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"2025122602495790200_ref11","doi-asserted-by":"publisher","first-page":"916","DOI":"10.4172\/2165-7920.1000916","article-title":"An unusual case of Grave\u2019s disease with primary Sclerosing cholangitis (PSC)","volume":"07","author":"Mashi","year":"2017","journal-title":"J Clin Case Rep"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/12\/omaf261\/66128221\/omaf261.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2025\/12\/omaf261\/66128221\/omaf261.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T07:50:06Z","timestamp":1766735406000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/doi\/10.1093\/omcr\/omaf261\/8404877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12,24]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omaf261","relation":{},"ISSN":["2053-8855"],"issn-type":[{"type":"electronic","value":"2053-8855"}],"subject":[],"published-other":{"date-parts":[[2025,12]]},"published":{"date-parts":[[2025,12]]},"article-number":"omaf261"}}