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The present report detailed the primary imaging abnormalities observed in the patient and highlighted the importance of considering a differential diagnosis within the context of the clinical picture The clinical approach supporting the inflammatory origin of the observed imaging abnormalities in this case is discussed. Furthermore, this case highlighted the rapid effect of cortiotherapy in improving the neurological dysfunctions associated with neurosarciodosis which can be life-threatening.<\/jats:p>","DOI":"10.1093\/omcr\/omaf284","type":"journal-article","created":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T12:32:37Z","timestamp":1765197157000},"source":"Crossref","is-referenced-by-count":0,"title":["Diffuse leptomeningeal enhancement with optic nerve involvement in a patient with intracranial hypertension as the inaugural symptom of neurosarcoidosis"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4115-8758","authenticated-orcid":false,"given":"Zakaria","family":"Saied","sequence":"first","affiliation":[{"name":"Department of Neurology, National Institute Mongi Ben Hamida of Neurology , Omar El Chedly Street, Bab Saadoun, Tunis city 1006 ,","place":["TUNISIA"]},{"name":"Faculty of Medicine of Tunis, Tunis El Manar University , Hssouna Ben Ayed Street - Bab Saadoun, Tunis city 1006 ,","place":["TUNISIA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6220-5974","authenticated-orcid":false,"given":"Amine","family":"Rachdi","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute Mongi Ben Hamida of Neurology , Omar El Chedly Street, Bab Saadoun, Tunis city 1006 ,","place":["TUNISIA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania","family":"Zouari","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute Mongi Ben Hamida of Neurology , Omar El Chedly Street, Bab Saadoun, Tunis city 1006 ,","place":["TUNISIA"]},{"name":"Faculty of Medicine of Tunis, Tunis El Manar University , Hssouna Ben Ayed Street - Bab Saadoun, Tunis city 1006 ,","place":["TUNISIA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nebli","family":"Fatma","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute Mongi Ben Hamida of Neurology , Omar El Chedly Street, Bab Saadoun, Tunis city 1006 ,","place":["TUNISIA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina Ben","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Department of Neurology, National Institute Mongi Ben Hamida of Neurology , Omar El Chedly Street, Bab Saadoun, Tunis city 1006 ,","place":["TUNISIA"]},{"name":"Faculty of Medicine of Tunis, Tunis El Manar University , Hssouna Ben Ayed Street - 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