{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T22:45:41Z","timestamp":1769381141021,"version":"3.49.0"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T00:00:00Z","timestamp":1769299200000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Waldenstr\u00f6m\u2019s Macroglobulinemia (WM) is a lymphoplasmacytic lymphoma which can rarely transform into diffuse large B cell lymphoma (DLBCL). Usually, the diagnosis of WM precedes DLBCL. A 79-year-old male presented to the hospital for worsening dysphagia and shortness of breath due to a rapidly growing base of tongue mass detected by CT scan. The mass was thought initially to be isolated DLBCL, though incidentally, markedly elevated IgM titers were noted. Biopsy of bone marrow and mass were consistent with histological transformation of WM to DLBCL. Response to treatment was assessed by the size of tongue mass on interval CT scans and IgM levels, both of which responded rapidly to chemotherapy. However, the patient developed early CNS relapse, consistent with the overall poor prognosis of transformed WM.<\/jats:p>","DOI":"10.1093\/omcr\/omaf290","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T13:10:57Z","timestamp":1765372257000},"source":"Crossref","is-referenced-by-count":0,"title":["A case of transformation of Waldenstr\u00f6m\u2019s Macroglobulinemia to diffuse large B cell lymphoma"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1263-6570","authenticated-orcid":false,"given":"Meher B","family":"Ali","sequence":"first","affiliation":[{"name":"Internal Medicine, University of Maryland Medical Center, \u00a0 22 S Greene St, Baltimore, Maryland, 21201 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathryn","family":"Kline","sequence":"additional","affiliation":[{"name":"Hematology-Oncology, University of Maryland Greenebaum Comprehensive Cancer Center , 22 S Greene St, Baltimore, Maryland, 21201 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,1,25]]},"reference":[{"key":"2026012509585204100_ref1","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1053\/j.seminhematol.2023.03.008","article-title":"The epidemiology of Waldenstr\u00f6m macroglobulinemia","volume":"60","author":"McMaster","year":"2023","journal-title":"Semin Hematol"},{"key":"2026012509585204100_ref2","doi-asserted-by":"publisher","first-page":"e2024061","DOI":"10.4084\/MJHID.2024.061","article-title":"Waldenstr\u00f6m Macroglobulinemia\u2014a state-of-the-art review: part 1: epidemiology, pathogenesis, clinicopathologic characteristics, differential diagnosis, risk stratification, and clinical problems","volume":"16","author":"Bibas","year":"2024","journal-title":"Mediterr J Hematol Infect Dis"},{"key":"2026012509585204100_ref3","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1309\/R01VXG46MFCDVNHL","article-title":"Diffuse large B-cell lymphoma occurring in patients with lymphoplasmacytic lymphoma\/Waldenstr\u00f6m macroglobulinemia: clinicopathologic features of 12 cases","volume":"120","author":"Lin","year":"2003","journal-title":"Am J Clin Pathol"},{"key":"2026012509585204100_ref4","doi-asserted-by":"publisher","first-page":"650","DOI":"10.3390\/hemato3040044","article-title":"Transformed Waldenstr\u00f6m macroglobulinemia: update on diagnosis, prognosis and treatment","volume":"3","author":"Durot","year":"2022","journal-title":"Hemato."},{"key":"2026012509585204100_ref5","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1111\/bjh.15049","article-title":"MYD88 wild-type Waldenstr\u00f6m macroglobulinemia: differential diagnosis, risk of histological transformation, and overall survival","volume":"180","author":"Treon","year":"2018","journal-title":"Br J Haematol"},{"key":"2026012509585204100_ref6","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1111\/bjh.14881","article-title":"Transformed Waldenstr\u00f6m macroglobulinaemia: clinical presentation and outcome. 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