{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T00:20:40Z","timestamp":1793578840009,"version":"4.5.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Dengue is an arbovirus with significant global prevalence that can lead to severe neurological complications, such as longitudinally extensive transverse myelitis (LEMT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case report<\/jats:title>\n                    <jats:p>We describe a 36-year-old man who developed sudden paraparesis and urinary retention approximately ten days after dengue infection. MRI revealed longitudinal hyperintense lesions in the cervical and thoracic spinal cord. Cerebrospinal fluid analysis revealed an inflammatory pattern and dengue serology was positive. The patient was treated with intravenous methylprednisolone and rehabilitation, leading to gradual neurological improvement and functional recovery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Post-dengue transverse myelitis may result from parainfectious or post-infectious autoimmune mechanisms, often accompanied by demyelination and spinal cord inflammation. The low rate of DENV IgM in the CSF reinforces the immune-mediated hypothesis. Prognosis varies depending on the early intervention and the extent of spinal injury. Underreporting remains a challenge, and future studies should explore biomarkers and develop standardized management protocols.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/omcr\/omag005","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T12:18:37Z","timestamp":1768220317000},"page":"148-150","source":"Crossref","is-referenced-by-count":2,"title":["Post-dengue transverse myelitis: a challenging case of neurological and therapeutic evidence"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5742-9836","authenticated-orcid":false,"given":"Bianca Frigo","family":"Pires","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Faculdade de Medicina de Mar\u00edlia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9632-243X","authenticated-orcid":false,"given":"Caroline Goulart Nunes","family":"de Souza","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5105-3399","authenticated-orcid":false,"given":"Eduardo Coviello Mendes","family":"de Campos","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9988-7790","authenticated-orcid":false,"given":"Talles","family":"Rajab","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9449-759X","authenticated-orcid":false,"given":"Mariana Ferreira","family":"de Albuquerque","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1225-6160","authenticated-orcid":false,"given":"Jo\u00e3o Victor Padovani do","family":"Carmo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4342-7497","authenticated-orcid":false,"given":"Fernanda Ferraioli","family":"de Paula","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0370-439X","authenticated-orcid":false,"given":"Luiz Guilherme","family":"Peleckis","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-1071-981X","authenticated-orcid":false,"given":"Bruno Tolentino","family":"Foroni","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-4480-6186","authenticated-orcid":false,"given":"Clara Luisa Negraes","family":"Navarrete","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3442-4818","authenticated-orcid":false,"given":"Fernanda Goulart Nunes","family":"de Souza","sequence":"additional","affiliation":[{"name":"Department of Neurology, Universidade Federal de S\u00e3o Carlos , Rodovia Washington Lu\u00eds, km 235, Monjolinho District, S\u00e3o Carlos \u2013 State of S\u00e3o Paulo, 13565-905 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3445-1817","authenticated-orcid":false,"given":"Gustavo Henrique","family":"de Moura Vardasca","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4634-1379","authenticated-orcid":false,"given":"Natalia Seno","family":"Croccia","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine of Marilia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7894-1391","authenticated-orcid":false,"given":"Raiza Marques Vieira","family":"Campos","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Universidade Federal do Amap\u00e1 , Rodovia Juscelino Kubitschek, km 02, Jardim Marco Zero District, Macap\u00e1 \u2013 State of Amap\u00e1, 68903-419 ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3232-2522","authenticated-orcid":false,"given":"Ruy Yoshiaki","family":"Okaji","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Faculdade de Medicina de Mar\u00edlia, Avenida Monte Carmelo, 800, Fragata District, Mar\u00edlia - State of S\u00e3o Paulo, 175190-30, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"2026022410590073100_ref1","doi-asserted-by":"publisher","first-page":"e54074","DOI":"10.7759\/cureus.54074","article-title":"Acute transverse myelitis as an unusual complication of dengue fever: a case report and literature review","volume":"16","author":"Karishma","year":"2024","journal-title":"Cureus."},{"key":"2026022410590073100_ref2","doi-asserted-by":"publisher","first-page":"e8461","DOI":"10.1002\/ccr3.8461","article-title":"An unusual case of transverse myelitis in dengue fever: a case report from Nepal","volume":"12","author":"Shrestha","year":"2024","journal-title":"Clin Case Rep"},{"key":"2026022410590073100_ref3","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1080\/10790268.2010.11689722","article-title":"Acute transverse myelitis associated with dengue viral infection","volume":"33","author":"Chanthamat","year":"2010","journal-title":"J Spinal Cord Med"},{"key":"2026022410590073100_ref4","doi-asserted-by":"publisher","first-page":"103206","DOI":"10.1016\/j.msard.2021.103206","article-title":"Longitudinally extensive transverse myelitis with positive aquaporin-4 IgG associated with dengue infection: a case report and systematic review of cases","volume":"55","author":"Comtois","year":"2021","journal-title":"Mult Scler Relat Disord"},{"key":"2026022410590073100_ref5","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.4103\/0028-3886.266296","article-title":"Dengue-related longitudinally extensive transverse myelitis","volume":"67","author":"Tan","year":"2019","journal-title":"Neurol India"},{"key":"2026022410590073100_ref6","doi-asserted-by":"publisher","first-page":"380","DOI":"10.4269\/ajtmh.16-0284","article-title":"Transverse myelitis as an unusual complication of dengue fever","volume":"96","author":"Mota","year":"2017","journal-title":"Am J Trop Med Hyg"},{"key":"2026022410590073100_ref7","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.msard.2017.12.013","article-title":"Myelitis and cauda equina involvement following dengue fever: a case report and review of the literature","volume":"20","author":"Lana-Peixoto","year":"2018","journal-title":"Mult Scler Relat Disord"},{"key":"2026022410590073100_ref8","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.jcv.2005.08.006","article-title":"Acute transverse myelitis following dengue virus infection","volume":"35","author":"Seet","year":"2006","journal-title":"J Clin Virol"},{"key":"2026022410590073100_ref9","doi-asserted-by":"publisher","first-page":"bcr1220115378","DOI":"10.1136\/bcr.12.2011.5378","article-title":"Longitudinally extensive transverse myelitis associated with dengue fever","volume":"2012","author":"Larik","year":"2012","journal-title":"BMJ Case Rep"},{"key":"2026022410590073100_ref10","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/j.tmaid.2013.11.001","article-title":"Neurological manifestations of dengue: a cross-sectional study","volume":"12","author":"Weeratunga","year":"2014","journal-title":"Travel Med Infect Dis"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2026\/2\/148\/67091970\/omag005.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/omcr\/article-pdf\/2026\/2\/148\/67091970\/omag005.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T15:59:09Z","timestamp":1771948749000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/2026\/2\/148\/8496120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2,18]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omag005","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,2]]},"published":{"date-parts":[[2026,2]]}}}