{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:14:45Z","timestamp":1777522485029,"version":"3.51.4"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T00:00:00Z","timestamp":1562889600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Here, we report the case of a 27-year-old woman with tuberous sclerosis complex who underwent successful endovascular intervention for cerebral venous thrombosis at the superior sagittal sinus. She had protein S deficiency and a long-term history of anemia caused by menorrhagia from uterine fibroids, possibly leading to a hypercoagulable state. Cerebral venous sinus thrombosis accounts for ~0.5\u20131% of all strokes. Several cases of venous thrombosis in patients with tuberous sclerosis complex and protein S or protein C deficiency have been reported, but further studies are needed to identify whether an association of this rare combination may be explained.<\/jats:p>","DOI":"10.1093\/omcr\/omz060","type":"journal-article","created":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T11:15:51Z","timestamp":1562930151000},"source":"Crossref","is-referenced-by-count":3,"title":["Successful endovascular recanalization of massive cerebral venous sinus thrombosis in a patient with tuberous sclerosis and protein S deficiency: a case report"],"prefix":"10.1093","volume":"2019","author":[{"given":"Yasuhiro","family":"Nishiyama","sequence":"first","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan"},{"name":"Department of Neurology, Nippon Medical School, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Ueda","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanako","family":"Muraga","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Medicine, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan"},{"name":"Department of Neurology, Nippon Medical School, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Ota","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Horikawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumi","family":"Kimura","sequence":"additional","affiliation":[{"name":"Department of Neurology, Nippon Medical School, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,7,12]]},"reference":[{"key":"2019071207154741100_ref1","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1161\/STR.0b013e31820a8364","article-title":"Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association\/American Stroke Association","volume":"42","author":"Saposnik","year":"2011","journal-title":"Stroke"},{"key":"2019071207154741100_ref2","doi-asserted-by":"crossref","first-page":"e13","DOI":"10.4081\/ni.2011.e13","article-title":"Cerebral venous thrombosis: diagnosis dilemma","volume":"3","author":"Chiewvit","year":"2011","journal-title":"Neurol 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cortical vein thrombosis with type II protein S deficiency: a case report","volume":"16","author":"Arai","year":"2016","journal-title":"BMC Neurol"},{"key":"2019071207154741100_ref7","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0049-3848(00)00337-6","article-title":"Frequency of protein S deficiency in general Japanese population","volume":"100","author":"Nomura","year":"2000","journal-title":"Thromb Res"},{"key":"2019071207154741100_ref8","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1046\/j.1365-2141.2001.02813.x","article-title":"A study of protein S antigen levels in 3788 healthy volunteers: influence of age, sex and hormone use, and estimate for prevalence of inherited thrombophilia","volume":"113","author":"Dykes","year":"2001","journal-title":"Br J Hematol"},{"key":"2019071207154741100_ref9","doi-asserted-by":"crossref","first-page":"E6","DOI":"10.3171\/2009.8.FOCUS09154","article-title":"A review of therapeutic strategies for the management of cerebral venous sinus thrombosis","volume":"27","author":"Medel","year":"2009","journal-title":"Neurosurg Focus"},{"key":"2019071207154741100_ref10","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1161\/STROKEAHA.114.007465","article-title":"Mechanical thrombectomy in cerebral venous thrombosis: systematic review of 185 cases","volume":"46","author":"Siddiqui","year":"2015","journal-title":"Stroke"}],"container-title":["Oxford Medical Case 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