{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:55:24Z","timestamp":1792803324441,"version":"4.5.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T00:00:00Z","timestamp":1575936000000},"content-version":"vor","delay-in-days":39,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Hematological malignancies need special attention in the intensive care unit (ICU). Leukemia has numerous presentations in the ICU. Most commonly, these patients present with complications of therapy. Infection and neutropenia are major reasons for ICU admission. Pulmonary complications in patients with leukemia are often due to pneumonia, hemorrhage, edema or drug toxicity; however, pulmonary leukemic infiltration is a well-known complication in all types of pneumonia but is not well described in chronic myelomonocytic leukemia. It can contribute to a rapid decline in respiratory status. Distinguishing among infection, pulmonary edema and leukemic infiltrates can be challenging. Characteristic radiological patterns have been described but are still challenging to recognize. Critical care management in these cases can have a large impact, and early intervention could be lifesaving in the appropriate clinical setting.<\/jats:p>","DOI":"10.1093\/omcr\/omz118","type":"journal-article","created":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T12:37:28Z","timestamp":1575981448000},"page":"482-485","source":"Crossref","is-referenced-by-count":7,"title":["Leukemic infiltration in the settings of acute respiratory failure"],"prefix":"10.1093","volume":"2019","author":[{"given":"M","family":"Fayed","sequence":"first","affiliation":[{"name":"Pulmonary Critical Care Division, UCSF Fresno, Fresno, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Evans","sequence":"additional","affiliation":[{"name":"Pulmonary Critical Care Division, UCSF Fresno, Fresno, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Abdulhaq","sequence":"additional","affiliation":[{"name":"Hematology Oncology, UCSF Fresno, Fresno, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,12,9]]},"reference":[{"key":"2019121007372250300_ref1","volume-title":"Harrison\u2019s Principles of Internal Medicine","author":"Tefferi","year":"2015","edition":"19th"},{"key":"2019121007372250300_ref2","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1080\/10428194.2016.1258700","article-title":"Incidence and survival outcomes of chronic myelomonocytic leukemia in the United States","volume":"58","author":"Guru Murthy","year":"2017","journal-title":"Leuk Lymphoma"},{"key":"2019121007372250300_ref3","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/S0025-6196(12)61287-7","article-title":"Chronic myelomonocytic leukemia: natural history and prognostic determinants","volume":"64","author":"Tefferi","year":"1989","journal-title":"Mayo Clin Proc"},{"key":"2019121007372250300_ref4","volume-title":"Thoracic Imaging: Pulmonary and Cardiovascular Radiology","author":"Webb","year":"2005"},{"key":"2019121007372250300_ref5","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1097\/00004424-198311000-00002","article-title":"Chest radiographic-pathologic correlation in adult leukemia patients","volume":"18","author":"Maile","year":"1983","journal-title":"Invest Radiol"},{"key":"2019121007372250300_ref6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ccm.2016.12.003","article-title":"Pulmonary manifestations of lymphoma and leukemia","volume":"38","author":"Bashoura","year":"2017","journal-title":"Clin Chest Med"},{"key":"2019121007372250300_ref7","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1002\/1097-0142(19870815)60:4<827::AID-CNCR2820600419>3.0.CO;2-A","article-title":"An autopsy study of 1206 acute and chronic leukemias (1958 to 1982)","volume":"60","author":"Barcos","year":"1987","journal-title":"Cancer"},{"key":"2019121007372250300_ref8","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/s003300101013","article-title":"CT findings of leukemic pulmonary infiltration with pathologic correlation","volume":"12","author":"Tanaka","year":"2002","journal-title":"Eur Radiol"},{"key":"2019121007372250300_ref9","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2214\/ajr.174.2.1740517","article-title":"Pulmonary leukemic infiltrates: high-resolution CT findings in 10 patients","volume":"174","author":"Heyneman","year":"2000","journal-title":"AJR Am J Roentgenol"},{"key":"2019121007372250300_ref10","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1159\/000225262","article-title":"An autopsy study of the metastatic patterns of human leukemias","volume":"35","author":"Viadana","year":"1978","journal-title":"Oncology"}],"container-title":["Oxford Medical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2019\/11\/482\/31335497\/omz118.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/omcr\/article-pdf\/2019\/11\/482\/31335497\/omz118.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,10]],"date-time":"2019-12-10T12:37:31Z","timestamp":1575981451000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/omcr\/article\/2019\/11\/482\/5670821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,1]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/omcr\/omz118","relation":{},"ISSN":["2053-8855"],"issn-type":[{"value":"2053-8855","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,11]]},"published":{"date-parts":[[2019,11,1]]}}}