{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:12:31Z","timestamp":1770883951722,"version":"3.50.1"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T00:00:00Z","timestamp":1719964800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Multiple myeloma (MM) is the second most common hematological malignancy with its prevalence increasing. Patients with symptomatic MM can show numerous comorbidities, affecting their quality of life (QoL). Physical activity (PA) may improve QoL but is not a standardized intervention of comprehensive cancer centers (CCCs). Since data on the PA of patients with MM are scarce, we aimed to prospectively assess fitness levels and patients\u2019 motivation to join PA-interventions at our CCC.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We generated an exercise questionnaire to interview consecutive patients MM. We prospectively collected data on (a) past and current PA, defined by the World Health Organization (WHO) recommendations, (b) knowledge on exercise effects, (c) exercise motivation, and (d) willingness to participate in PA-interventions. Demographics, comorbidities, response, progression-free survival (PFS), and overall survival (OS) were assessed in 211 symptomatic patients MM.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>While our patients were elderly and most showed bone involvement, their PA was similar to healthy individuals. Aerobic PA (\u2265\u200560 minutes\/week) was performed by 65%, and 25% exercised\u2005\u2265\u2005150 minutes\/week. WHO PA recommendations were fulfilled by 17% of patients. No sport activities or complete physical inactivity were observed in 35% and 16%, respectively. Notably, 38% were motivated to join MM-specific sport interventions. Self-reported knowledge of PA-induced benefits for patients cancer was high (82%), but only 27% knew which exercises were safe to perform.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This study provides an overview of the PA of patients MM. Our results suggest that the PA of patients MM might not be much lower than in the age-matched general population.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/oncolo\/oyae111","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T01:31:43Z","timestamp":1719970303000},"page":"e1336-e1346","source":"Crossref","is-referenced-by-count":5,"title":["Physical activity and exercise motivation of multiple myeloma patients: a prospective cross-sectional study"],"prefix":"10.1093","volume":"29","author":[{"given":"Jan","family":"R\u00e4der","sequence":"first","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Comprehensive Cancer Center Freiburg, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Ihorst","sequence":"additional","affiliation":[{"name":"Clinical Trials Unit, Biometry and Statistics, Faculty of Medicine, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandy-Deborah","family":"M\u00f6ller","sequence":"additional","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Comprehensive Cancer Center Freiburg, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonia","family":"Pahl","sequence":"additional","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Greil","sequence":"additional","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Comprehensive Cancer Center Freiburg, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Dreyling","sequence":"additional","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Comprehensive Cancer Center Freiburg, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jann","family":"Arends","sequence":"additional","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Comprehensive Cancer Center Freiburg, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Deibert","sequence":"additional","affiliation":[{"name":"Department of Medicine, Medical Center University of Freiburg, Faculty of Medicine, Institute for Exercise and Occupational Medicine, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph","family":"W\u00e4sch","sequence":"additional","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Comprehensive Cancer Center Freiburg, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0405-1676","authenticated-orcid":false,"given":"Monika","family":"Engelhardt","sequence":"additional","affiliation":[{"name":"Department of Medicine I Hematology and Oncology, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Comprehensive Cancer Center Freiburg, Faculty of Medicine and Medical Center, University of Freiburg , 79106 Freiburg ,","place":["Germany"]},{"name":"Clinical Trials Unit, Biometry and Statistics, Faculty of Medicine, University of Freiburg , 79106 Freiburg 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