{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T12:29:48Z","timestamp":1764937788001,"version":"3.41.2"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"crossref","award":["FIS PI19\/01476","FIS PI22\/01660"],"award-info":[{"award-number":["FIS PI19\/01476","FIS PI22\/01660"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Spanish Ministry of Education"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The 2022 WHO revision and the ICC classification have recently modified the diagnostic criteria for chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia. However, there is no consensus on whether CMML with NPM1 mutation (NPM1mut) should be diagnosed as AML. Nowadays, it is a subject of discussion because of its diagnostic and therapeutic implications. Therefore, we describe a case of a patient diagnosed with CMML NPM1mut and briefly review the literature to highlight the uncertainty about how to classify a CMML with NPM1 mutation. We emphasize the importance of a comprehensive molecular study, which is crucial to optimize the individualized treatment of patients, enabling them to access targeted therapies.<\/jats:p>","DOI":"10.1093\/oncolo\/oyae246","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T02:40:56Z","timestamp":1727750456000},"source":"Crossref","is-referenced-by-count":2,"title":["Chronic myelomonocytic leukemia with <i>NPM1<\/i> mutation or acute myeloid leukemia?"],"prefix":"10.1093","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9044-4665","authenticated-orcid":false,"given":"Sandra","family":"Casta\u00f1o-D\u00edez","sequence":"first","affiliation":[{"name":"Hematology Department, Hospital Cl\u00ednic Barcelona , Barcelona ,\u00a0","place":["Spain"]},{"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) , Barcelona ,","place":["Spain"]},{"name":"Universitat Barcelona , Barcelona ,\u00a0","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Ram\u00f3n","family":"\u00c1lamo","sequence":"additional","affiliation":[{"name":"Hematopathology Section, Pathology Department, Hospital Cl\u00ednic Barcelona , Barcelona ,\u00a0","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f2nica","family":"L\u00f3pez-Guerra","sequence":"additional","affiliation":[{"name":"Institut d\u2019Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS) , Barcelona ,","place":["Spain"]},{"name":"Hematopathology Section, Pathology Department, Hospital Cl\u00ednic Barcelona , Barcelona ,\u00a0","place":["Spain"]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de C\u00e1ncer (CIBERONC) , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"G\u00f3mez-Hernando","sequence":"additional","affiliation":[{"name":"Hematopathology Section, Pathology 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