{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:19:00Z","timestamp":1790731140257,"version":"4.1.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"National Center for Tumor Diseases Heidelberg"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>The incidence of colorectal carcinoma (CRC) in patients \u226450 (early-onset-CRC, EOCRC) years is increasing. Given their different phase of life, younger individuals may face specific challenges in terms of body image, professional life, and psychosocial support. However, tailored programs for EOCRC patients are lacking in Germany. JUMP-START, a prospective study at the National Center for Tumor Diseases (NCT) Heidelberg in collaboration with the AIO (Arbeitsgemeinschaft internistische Onkologie) and the foundation for young adults with cancer in Germany aims to identify the specific needs of EOCRC patients and improve multiprofessional care.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Materials and Methods<\/jats:title>\n                  <jats:p>Semi-structured interviews were conducted until content saturation, based on an interview guide focused on challenges related to diagnosis, utilization of support programs, and unmet needs. The interview guide was developed in an expert and patient panelist discussion. Qualitative analysis was performed with MAXQDA, using a content structuring qualitative content analysis according to Kuckartz.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Forty-three EOCRC patients were screened, and 14 participants were interviewed at NCT Heidelberg between October 2023 and January 2024. Three main themes emerged: (1) The impact of CRC diagnosis at an early age on psychological and physical health, daily routine, and future perspectives, (2) Experiences with care service access and utility, and (3) Expectations for a multiprofessional care at a dedicated EOCRC center.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>EOCRC patients highlighted various age-group-specific challenges related to diagnosis and treatment. Tailored multiprofessional programs may optimize care for EOCRC patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/oncolo\/oyaf082","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T11:36:05Z","timestamp":1748345765000},"source":"Crossref","is-referenced-by-count":4,"title":["Optimization of multiprofessional care for young colorectal cancer patients: a qualitative Study"],"prefix":"10.1093","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5595-7787","authenticated-orcid":false,"given":"Kaiyu","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital , Heidelberg 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,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantin","family":"Bienen","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Walther","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Robl","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital , Heidelberg 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Diseases (NCT) Heidelberg, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"Clinical Cooperation Unit Applied Tumor-Immunity, German Cancer Research Center (DKFZ) , Heidelberg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5830-3616","authenticated-orcid":false,"given":"Paula","family":"Hoffmeister-Wittmann","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9410-9968","authenticated-orcid":false,"given":"Georg Martin","family":"Haag","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg University Hospital , Heidelberg ,","place":["Germany"]},{"name":"Clinical 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