{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:11:36Z","timestamp":1790140296977,"version":"4.0.1"},"reference-count":6,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T00:00:00Z","timestamp":1758672000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA256660"],"award-info":[{"award-number":["R01CA256660"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Women with a history of vulvar cancer face a high risk of anal cancer; however, incidence according to histology, age-at, and time since vulvar cancer diagnosis remains unexplored. Using data from SEER-8 and SEER-17 registries, we identified 21,230 women with vulvar cancer, with 154,825 person-years follow-up from 1975 to 2021. We observed 95 anal cancer cases, resulting in an incidence of 61.4 per 100,000 person-years (95% CI, 49.6-75.0). Incidence was higher among women with vulvar squamous cell carcinoma (SCC) (78.7; 95% CI, 62.9-97.1) than vulvar non-SCC (19.8; 95% CI, 9.0-37.6). The highest incidence (&amp;gt;100 per 100,000) was observed in women &amp;lt;45\u2009years old with vulvar SCC and those &amp;gt;10\u2009years post-diagnosis. These findings could inform anal cancer screening guidelines, as women with vulvar cancer, particularly those diagnosed with SCC, may substantially benefit from heightened surveillance or targeted screening.<\/jats:p>","DOI":"10.1093\/oncolo\/oyaf307","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T14:06:28Z","timestamp":1758722788000},"source":"Crossref","is-referenced-by-count":3,"title":["Anal cancer incidence among women with a history of vulvar cancer by histology, age, and time since diagnosis"],"prefix":"10.1093","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4361-4515","authenticated-orcid":false,"given":"Haluk","family":"Damgacioglu","sequence":"first","affiliation":[{"name":"Department of Public Health Sciences, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]},{"name":"Cancer Control Program, Hollings Cancer Center, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5501-3034","authenticated-orcid":false,"given":"Kalyani","family":"Sonawane","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]},{"name":"Cancer Control Program, Hollings Cancer Center, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary M","family":"Clifford","sequence":"additional","affiliation":[{"name":"Early Detection, Prevention and Infections, International Agency of Research on Cancer , Lyon 69007,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel M","family":"Palefsky","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of California at San Francisco , San Francisco, CA 94143,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gweneth B","family":"Lazenby","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian C","family":"Orr","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane R","family":"Montealegre","sequence":"additional","affiliation":[{"name":"Department of Behavioral Science, The University of Texas MD Anderson Cancer Center , Houston, TX 77030,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth Y","family":"Chiao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, MD Anderson Cancer Center , Houston, TX 77030,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith M","family":"Sigel","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, Mt Sinai Icahn School of Medicine , New York, NY 10029,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish A","family":"Deshmukh","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]},{"name":"Cancer Control Program, Hollings Cancer Center, Medical University of South Carolina , Charleston, SC 29425,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"key":"2025101312313940000_oyaf307-B1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1002\/ijc.33185","article-title":"A meta-analysis of anal cancer incidence by risk group: toward a unified anal cancer risk scale","volume":"148","author":"Clifford","year":"2021","journal-title":"Int J Cancer"},{"key":"2025101312313940000_oyaf307-B2","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1002\/ijc.34850","article-title":"International anal neoplasia society\u2019s consensus guidelines for anal cancer screening","volume":"154","author":"Stier","year":"2024","journal-title":"Int J Cancer"},{"key":"2025101312313940000_oyaf307-B3","author":"Surveillance, Epidemiology, and End Results (SEER) Program"},{"key":"2025101312313940000_oyaf307-B4","author":"Surveillance, Epidemiology, and End Results (SEER) Program"},{"key":"2025101312313940000_oyaf307-B5","first-page":"1358","article-title":"Multiple primary malignant tumors. a survey of the literature and a statistical study","volume":"16","author":"Warren","year":"1932","journal-title":"Am J Cancer"},{"key":"2025101312313940000_oyaf307-B6","doi-asserted-by":"crossref","first-page":"975","DOI":"10.7326\/ANNALS-24-01426","article-title":"Screening for anal cancer among men who have sex with men with HIV: benefits, harms, and Cost-Effectiveness analyses","volume":"178","author":"Deshmukh","year":"2025","journal-title":"Ann Intern Med"}],"container-title":["The 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