{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T13:07:11Z","timestamp":1785157631282,"version":"3.55.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["K12AR84222"],"award-info":[{"award-number":["K12AR84222"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["UL1TR002377"],"award-info":[{"award-number":["UL1TR002377"]}],"id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anxiety is a common symptom experienced by patients with cancer, who are increasingly interested in non-pharmacologic symptom management. Acupressure, a noninvasive intervention thought to impact the neurohormonal axis, has shown promise in reducing anxiety. However, research on acupressure for anxiety in patients with cancer has been limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Individuals receiving chemotherapy, who reported baseline anxiety, were eligible for this study. Consenting participants received one 15-minute nurse-led acupressure session and completed pre- and post-intervention surveys. The primary endpoint was a change in anxiety. Participants were also asked about symptoms of nausea, pain, well-being, relaxation, worry, and distress. Participants were invited to learn self-acupressure techniques. These participants were asked to complete a final survey 1-week post-intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty adult patients participated in this study. Mean baseline anxiety was 5 on a 0 to 10 Likert scale. Immediate post-intervention anxiety scores significantly improved for all thirty patients to an average of 2.0 (P\u2009&amp;lt;\u2009.001). Mean nausea scores improved from 1.5 at baseline to 0 post-intervention (P\u2009&amp;lt;\u2009.001), and pain scores improved from 2.0 at baseline to 1.0 post-intervention (P\u2009=\u2009.001). Participants reported significant improvement in sense of wellbeing (P\u2009=\u2009.0004), distress (P\u2009&amp;lt;\u2009.001), ability to achieve relaxation (P\u2009&amp;lt;\u2009.001), and ability to control their worries (P\u2009&amp;lt;\u2009.001). The improvement in anxiety, well-being, and relaxation was sustained at one week. 100% of participants stated that they would recommend acupressure for symptom management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Acupressure is a promising non-pharmacologic intervention for the management of cancer-associated anxiety.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/oncolo\/oyag166","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:34:52Z","timestamp":1777376092000},"source":"Crossref","is-referenced-by-count":0,"title":["Acupressure for anxiety: a pilot study of a nurse-led acupressure intervention for patients receiving chemotherapy"],"prefix":"10.1093","volume":"31","author":[{"given":"Laura","family":"Rhee","sequence":"first","affiliation":[{"name":"Division of Community, Internal Medicine, Geriatrics, and Palliative Care Mayo Clinic, , 200 First St SW , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Cutshall","sequence":"additional","affiliation":[{"name":"Division of Community, Internal Medicine, Geriatrics, and Palliative Care Mayo Clinic, , 200 First St SW , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbey","family":"Metzger","sequence":"additional","affiliation":[{"name":"Division of Community, Internal Medicine, Geriatrics, and Palliative Care Mayo Clinic, , 200 First St SW , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Kruger","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Mayo Clinic, , 200 First St SW , Rochester, MN 55905,","place":["United 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First St SW , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6298-332X","authenticated-orcid":false,"given":"Kathryn","family":"Ruddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles L","family":"Loprinzi","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Mayo Clinic, , 200 First St SW , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen M","family":"Fischer","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Mayo Clinic, , 200 First St SW , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenn M","family":"Manggaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3532-4913","authenticated-orcid":false,"given":"Elizabeth","family":"Cathcart-Rake","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Mayo Clinic, , 200 First St SW , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"2026072708570220500_oyag166-B1","doi-asserted-by":"publisher","first-page":"1261","DOI":"10.1054\/bjoc.2000.1405","article-title":"Anxiety in cancer patients","volume":"83","author":"Stark","year":"2000","journal-title":"Br J Cancer"},{"key":"2026072708570220500_oyag166-B2","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/S1470-2045(11)70002-X","article-title":"Prevalence of depression, anxiety, and adjustment disorder in oncological, 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